1384440-57-6

Basic information

• Product Name: 3,5-diformyl-4-hydroxybenzoic acid
• Synonyms: 3,5-diformyl-4-hydroxybenzoic acid
• CAS NO: 1384440-57-6
• Molecular Weight: 194.144
• Mol File: 1384440-57-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 3,5-diformyl-4-hydroxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-diformyl-4-hydroxybenzoic acid(1384440-57-6)
• EPA Substance Registry System: 3,5-diformyl-4-hydroxybenzoic acid(1384440-57-6)

Safety Data

• Hazardous Substances Data: 1384440-57-6(Hazardous Substances Data)

Upstream product

• 328030-95-1 3,5-diformyl-4-hydroxybenzoic acid methyl ester 
• 76-05-1 trifluoroacetic acid 
• 99-96-7 4-hydroxy-benzoic acid 
• 100-97-0 hexamethylenetetramine 

Relevant articles and documents

Dicopper(II) Complexes of p-Cresol-2,6-Bis(dpa) Amide-Tether Ligands: Large Enhancement of Oxidative DNA Cleavage, Cytotoxicity, and Mechanistic Insight by Intracellular Visualization

Dicopper complexes of a new p-cresol-2,6-bis(dpa) amide-tether ligand (HL1), [Cu2(μ-OH2)(μ-1,3-OAc)(L1)](ClO4)2 (1) and [Cu2(μ-1,1-OAc)(μ-1,3-OAc)(L1)]X (X = ClO4 (2a), OAc (2b)) were synthesized and structurally characterized. 2b rapidly cleaves supercoiled plasmid DNA by activating H2O2 at neutral pH to a linear DNA and shows remarkable cytotoxicity in comparison with related complexes. As 2b is more cytotoxic than HL1, the dicopper core is kept in the cell. A boron dipyrromethene (Bodipy)-modified complex of the p-cresol-2,6-bis(dpa) amide-tether ligand having a Bodipy pendant (HL2), [Cu2(μ-OAc)2(L2)](OAc) (3), was synthesized to visualize intracellular behavior, suggesting that 2b attacks the nucleolus and mitochondria. A comet assay clearly shows that 2b does not cleave nuclear DNA. The apoptotic cell death is evidenced from flow cytometry.

A rare 4-fold interpenetrated metal-organic framework constructed from an anionic indium-based node and a cationic dicopper linker

A unique 4-fold interpenetrated metal-organic framework, TIF-1, was synthesized by combining an anionic indium node with a cationic linker. This framework shows a rare type of 4-fold interpenetrated dia network, constructed from tessellation of biangular and tetragonal type metal-organic micropores. The porosity of TIF-1 is moderate due to four-fold interpenetration and charge-balancing anions. The cationic feature of this MOF may give good efficiency for selective small anion exchange or separation. In addition, the thermal stability and moderate CO2 adsorption property of the complex were studied.

DINUCLEATING LIGAND OR DINUCLEAR METAL COMPLEX

To provide a dinuclear metal complex that can be synthesized simply and easily and has a proper anticancer action.SOLUTION: The present disclosure provides a dinucleating ligand represented by the following formula (I) and a dinuclear metal complex thereof (where each X may be the same or different to represent H, Cl, OMe, or, Me, Y is H, a phenyl group, a substituted carbamoyl group or the like).SELECTED DRAWING: None