138485-30-0

Basic information

• Product Name: 2-(4-FLUOROPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER
• Synonyms: 2-(4-FLUOROPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER
• CAS NO: 138485-30-0
• Molecular Formula: C₁₁H₁₁FO₄
• Molecular Weight: 226.202
• Mol File: 138485-30-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-FLUOROPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-FLUOROPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER(138485-30-0)
• EPA Substance Registry System: 2-(4-FLUOROPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER(138485-30-0)

Safety Data

• Hazardous Substances Data: 138485-30-0(Hazardous Substances Data)

Usage

Compound class

Fluoroaromatic compounds

Physical state

Colorless liquid

Derivation

Combination of 4-fluorophenyl and propanedioic acid

Usage

Chemical research, building block for synthesis of complex organic compounds

Industrial applications

Unique chemical properties

Safety precautions

Handle with care and follow safety guidelines due to potential hazards when mishandled.

Upstream product

• 553-90-2 Dimethyl oxalate 
• 34837-84-8 4-fluorobenzeneacetic acid methyl ester 
• 405-50-5 p-Fluorophenylacetic acid 
• 616-38-6 carbonic acid dimethyl ester 

Downstream Products

• 1401354-92-4 C₂₄H₂₆FNO₃ 
• 1401355-04-1 C₂₄H₂₆FNO₃ 
• 1401354-80-0 α-tert-butoxycarbonyl-α-(4-fluorophenyl)-γ-methylidene-δ-valerolactone 
• 138485-62-8 3-(4-Fluoro-phenyl)-4-hydroxy-6-methyl-1H-pyridin-2-one 
• 145983-06-8 α-(p-fluorophenyl)-α-methylmalonic acid 
• 150360-26-2 (2R)-2-(4-fluorophenyl)propanoic acid 
• 138485-35-5 5-(4-Fluoro-phenyl)-4-hydroxy-2-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid ethyl ester 

Relevant articles and documents

Gold(I)-Catalyzed Enantioselective Desymmetrization of 1,3-Diols through Intramolecular Hydroalkoxylation of Allenes

A gold(I)-catalyzed enantioselective desymmetrization of 1,3-diols was achieved by intramolecular hydroalkoxylation of allenes. The catalyst system 3-F-dppe(AuCl)2 /(R)-C8-TRIPAg proved to be specifically efficient to promote the desymmetrizing cyclization of 2-aryl-1,3-diols, which have proven challenging substrates in previous reports. Multisubstituted tetrahydrofurans were prepared in good yield with good enantioselectivity and diastereoselectivity by this method.

Microbial asymmetric decarboxylation of fluorine-containing arylmalonic acid derivatives

α-Methyl-α-(trifluoromethylphenyl)malonic acids have been incubated with Alcaligenes bronchisepticus to afford optically active α-arylpropionic acids.Generally, the chemical and optical yields of the reaction products were higher when the substituents on the aromatic ring were strongly electron-withdrawing.Decarboxylation of α-fluoro-α-phenylmalonic acid with the aid of the same bacterium afforded optically active α-fluoro-α-phenylacetic acid.