138745-99-0 Usage
Description
(2-PYRIDIN-3-YL-1,3-THIAZOL-4-YL)METHANOL is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its unique chemical structure, which includes a pyridinyl-thiazole framework attached to a hydroxymethyl group. This structure endows it with specific reactivity and properties that make it valuable in the development of novel therapeutic agents.
Uses
Used in Pharmaceutical Industry:
(2-PYRIDIN-3-YL-1,3-THIAZOL-4-YL)METHANOL is used as a chemical intermediate for the preparation of imidazothiadiazole and imidazopyridazine derivatives and analogs. These compounds are known as PAR4 antagonists, which are useful in the development of selective platelet aggregation inhibitors. By modulating the activity of PAR4 receptors, these antagonists can potentially be employed in the treatment of various conditions related to platelet aggregation and blood clotting, such as thrombosis and cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 138745-99-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,7,4 and 5 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 138745-99:
(8*1)+(7*3)+(6*8)+(5*7)+(4*4)+(3*5)+(2*9)+(1*9)=170
170 % 10 = 0
So 138745-99-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2OS/c12-5-8-6-13-9(11-8)7-2-1-3-10-4-7/h1-4,6,12H,5H2
138745-99-0Relevant articles and documents
HIV protease inhibiting compounds
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Page/Page column 122, (2010/02/12)
A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
Lactol PAF antagonists
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, (2008/06/13)
The invention encompasses compounds of general formula I: STR1 wherein W represents an imidazo[4,5-c]pyridyl group, optionally substituted with one or more substituents selected from C1 -C6 alkyl, C1 -C6 alkoxy, halo, CF, and CN; and Z, R1, R2, R3, R4, R5, R6 are variables. These compounds are useful as antagonists of platelet activating factor.
