13879-47-5

Basic information

• Product Name: S-benzyl O,O-diphenyl phosphorothiolate
• Synonyms: S-benzyl O,O-diphenyl phosphorothiolate
• CAS NO: 13879-47-5
• Molecular Weight: 356.382
• Mol File: 13879-47-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: S-benzyl O,O-diphenyl phosphorothiolate(CAS DataBase Reference)
• NIST Chemistry Reference: S-benzyl O,O-diphenyl phosphorothiolate(13879-47-5)
• EPA Substance Registry System: S-benzyl O,O-diphenyl phosphorothiolate(13879-47-5)

Safety Data

• Hazardous Substances Data: 13879-47-5(Hazardous Substances Data)

Upstream product

• 150-60-7 dibenzyl disulphide 
• 4712-55-4 diphenyl hydrogen phosphite 
• 100-53-8 phenylmethanethiol 
• 6313-36-6 benzyl thiosulphate 

Relevant articles and documents

NHC-Catalyzed Metathesis and Phosphorylation Reactions of Disulfides: Development and Mechanistic Insights

The development of efficient methods for the metathesis and phosphorylation reactions of disulfide compounds is of widespread interest due to their important synthetic utility in polymer, biological, medicinal and agricultural chemistry. Herein, we demonstrate the use of N-heterocyclic carbenes (NHCs) as versatile organocatalysts to promote these challenging reactions under mild conditions. This metal- and oxidant-free protocol is operationally simple with very short reaction times. The interplay between the nucleophilicity and basicity of NHCs in these reactions were also elucidated by NMR studies and high-level ab initio calculations.

N-Chlorosuccinimide-promoted synthesis of thiophosphates from thiols and phosphonates under mild conditions

A very simple N-chlorosuccinimide-promoted synthesis of thiophosphates through the coupling of thiols and phosphonates is reported. Notably, the reactions were carried out in the absence of a base. Functional groups including fluoro, bromo and trifluoromethyl are all tolerated by the reaction conditions employed. Both aryl and alkyl thiols are coupled smoothly with a broad spectrum of phosphonates to afford the corresponding thiophosphates in good to excellent yields.