139-06-0 Usage
Description
Calcium bis(cyclohexylsulphamate), also known as cyclamate calcium, is a white crystalline or powdery substance with a nearly odorless and very sweet taste. It is a nonnutritive sweetener that is approximately 30 times sweeter than sucrose. It is freely soluble in water, with neutral solutions to litmus, and almost insoluble in alcohol, benzene, chloroform, and ether. Its pH in a 10% solution ranges from 5.5 to 7.5.
Uses
Used in the Food Industry:
Calcium bis(cyclohexylsulphamate) is used as a nonnutritive sweetener for its high sweetness potency, which is approximately 30 times that of sucrose. It is particularly useful in the food industry for creating low-calorie or sugar-free products, catering to health-conscious consumers and those with diabetes.
Used in Citrus Agriculture:
In the agricultural sector, specifically for citrus farming, Calcium bis(cyclohexylsulphamate) is used as a method for regulating citrus summer light by managing cyclamate calcium nutrition. This application helps optimize the growth and development of citrus plants, potentially leading to better yields and fruit quality.
Please note that the provided materials do not mention any other specific industries or applications for Calcium bis(cyclohexylsulphamate). The information given focuses on its use as a nonnutritive sweetener and its application in citrus agriculture.
Originator
Sucaryl Calcium,Abbott,US,1953
Manufacturing Process
220 parts by weight, 2.22 mols, of cyclohexylamine and 57 parts by weight,
0,50 mol, of ammonium sulfamate were mixed at room temperature and
heated with agitation. At the end of one-half hour of heating the temperature
had reached 110°C and approximately one-half mol of ammonia had been
evolved. Heating was continued under reflux at 133°C for 22 additional hours.
A second half-mol of ammonia was liberated. The ammonia yield was 100%.The reaction mixture was cooled to 100°C. To the mixture was added a water
slurry containing 20.3 parts by weight, 0.55 equivalent, of calcium hydroxide
and 700 parts by weight of water. Cyclohexylamine was then removed by
azeotropic distillation with water.The amine which was recovered can be reused after drying.The residue from the distillation was evaporated to dryness in a vacuum oven
at 50°C and the resulting product analyzed. The product weighing 105.5 parts
by weight, 0.488 equivalent, was obtained which is a 98% yield of the
technical calcium cyclohexylsulfamate dihydrate.
Therapeutic Function
Pharmaceutic aid
Hazard
Not permitted for use in foods and soft
drinks, because of suspected carcinogenicity.
Safety Profile
Poison by ingestion and
intravenous routes. Experimental
reproductive effects. Questionable
carcinogen with experimental tumorigenic
and neoplastigenic data. Human mutation
data reported. When heated to
decomposition it emits very toxic fumes of
SO, and NO,. See also CALCIUM
COMPOUNDS.
Check Digit Verification of cas no
The CAS Registry Mumber 139-06-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 139-06:
(5*1)+(4*3)+(3*9)+(2*0)+(1*6)=50
50 % 10 = 0
So 139-06-0 is a valid CAS Registry Number.
InChI:InChI=1/2C6H13NO3S.Ca/c2*8-11(9,10)7-6-4-2-1-3-5-6;/h2*6-7H,1-5H2,(H,8,9,10);/q;;+2/p-2
