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13909-17-6

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13909-17-6 Usage

Description

1-(2-chloroethyl)-3-(4-fluorophenyl)-1-nitrosourea, commonly known as lomustine, is a chemotherapy drug that belongs to the class of alkylating agents. It is characterized by its nitrosourea functional group, which is responsible for its anti-cancer properties. 1-(2-chloroethyl)-3-(4-fluorophenyl)-1-nitrosourea also features a 2-chloroethyl and a 4-fluorophenyl group, which contribute to its pharmacological effects. Lomustine is used in the treatment of various types of cancer, including brain tumors and Hodgkin's lymphoma.

Uses

Used in Oncology:
Lomustine is used as an anticancer agent for the treatment of various types of cancer, such as brain tumors and Hodgkin's lymphoma. It functions by inhibiting the growth of cancer cells through its alkylating action. However, it is essential to use lomustine under the supervision of a healthcare professional due to its potential side effects, which may include bone marrow suppression, liver toxicity, and lung complications.
Used in Pharmaceutical Research:
In addition to its direct application in cancer treatment, lomustine is also used as a subject of pharmaceutical research to better understand its mechanism of action and to develop new, potentially less toxic, cancer treatments based on its chemical structure and properties.

Check Digit Verification of cas no

The CAS Registry Mumber 13909-17-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13909-17:
(7*1)+(6*3)+(5*9)+(4*0)+(3*9)+(2*1)+(1*7)=106
106 % 10 = 6
So 13909-17-6 is a valid CAS Registry Number.

13909-17-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-(4-fluorophenyl)-1-nitrosourea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13909-17-6 SDS

13909-17-6Downstream Products

13909-17-6Relevant articles and documents

The synthesis of potential anticancer agents. XXXVI. N-nitrosoureas. II. Haloalkyl derivatives.

Johnston,McCaleb,Opliger,Montgomery

, p. 892 - 911 (2007/10/05)

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