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13909-22-3

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13909-22-3 Usage

Description

1-(2-chloroethyl)-3-(4-cyanophenyl)-1-nitrosourea, commonly known as CCNU, is a chemotherapeutic agent characterized by its alkylating properties. It is derived from the nitrosourea class and is known for its ability to disrupt the DNA structure of cancer cells, leading to cell death. CCNU demonstrates significant antineoplastic activity by inhibiting tumor growth and promoting apoptosis in cancer cells.

Uses

Used in Oncology:
CCNU is utilized as an anticancer agent for the treatment of various types of cancer, including brain tumors and lymphoma. It functions by alkyating and damaging the DNA of cancer cells, which in turn inhibits their growth and induces apoptosis. This makes CCNU a valuable component in the arsenal of treatments for cancer patients.
Used in Pharmaceutical Research:
In the field of pharmaceutical research, CCNU is investigated for its potential applications in developing new cancer therapies. Its alkylating mechanism of action provides a foundation for designing and synthesizing novel compounds with improved efficacy and reduced side effects.
Used in Drug Delivery Systems:
Similar to gallotannin, CCNU can also benefit from advancements in drug delivery systems. Researchers are exploring the use of various organic and metallic nanoparticles as carriers for CCNU, aiming to enhance its delivery, bioavailability, and therapeutic outcomes in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 13909-22-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13909-22:
(7*1)+(6*3)+(5*9)+(4*0)+(3*9)+(2*2)+(1*2)=103
103 % 10 = 3
So 13909-22-3 is a valid CAS Registry Number.

13909-22-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-(4-cyanophenyl)-1-nitrosourea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13909-22-3 SDS

13909-22-3Downstream Products

13909-22-3Relevant articles and documents

The synthesis of potential anticancer agents. XXXVI. N-nitrosoureas. II. Haloalkyl derivatives.

Johnston,McCaleb,Opliger,Montgomery

, p. 892 - 911 (2007/10/05)

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