139115-91-6 Usage
Description
2-(2-BOC-AMINOETHOXY)ETHANOL, also known as N-Boc-PEG2-alcohol, is a PEG linker containing a hydroxyl group and Boc-protected amino group. It is characterized by its hydrophilic PEG spacer, which increases solubility in aqueous media, and the hydroxyl group that allows for further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
Used in Bioconjugation and Molecular Recognition:
2-(2-BOC-AMINOETHOXY)ETHANOL is used as a molecular spacer/linker for the synthesis of biotinylated HaloLigands. This application enables the preparation of quantum dot adducts for HaloTag protein-mediated specific labeling of live cells, allowing for precise targeting and imaging of cellular components.
Used in Total Synthesis of Bioactive Compounds:
In the field of chemical synthesis, 2-(2-BOC-AMINOETHOXY)ETHANOL serves as a key precursor for the total synthesis of tyroscherin and photo-activatable tyroscherin-based affinity reagents. These reagents are utilized for the identification of tyroscherin binding proteins, contributing to the understanding of protein interactions and potential therapeutic targets.
Used in Cellular Zinc Dynamics Monitoring:
2-(2-BOC-AMINOETHOXY)ETHANOL is employed to link the HaloTag enzyme with fluorescent zinc indicator, ZIMIR. This application allows for the real-time monitoring of the dynamics of regulated secretion of zinc, providing insights into cellular processes and potential roles of zinc in various biological functions.
Used in Drug Delivery Systems:
In the pharmaceutical industry, 2-(2-BOC-AMINOETHOXY)ETHANOL can be used to synthesize amphiphiles for the delivery of DNA and siRNA. These amphiphiles can enhance the delivery, bioavailability, and therapeutic outcomes of genetic materials, potentially improving the efficacy of gene therapy and other nucleic acid-based treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 139115-91-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,1,1 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 139115-91:
(8*1)+(7*3)+(6*9)+(5*1)+(4*1)+(3*5)+(2*9)+(1*1)=126
126 % 10 = 6
So 139115-91-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H19NO4/c1-9(2,3)14-8(12)10-4-6-13-7-5-11/h11H,4-7H2,1-3H3,(H,10,12)
