1391930-67-8

Basic information

• Product Name: 1-methyl-3-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]tetrahydropyrimidin-2(1H)-one
• Synonyms: 1-methyl-3-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]tetrahydropyrimidin-2(1H)-one
• CAS NO: 1391930-67-8
• Molecular Weight: 254.137
• Mol File: 1391930-67-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl-3-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]tetrahydropyrimidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-3-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]tetrahydropyrimidin-2(1H)-one(1391930-67-8)
• EPA Substance Registry System: 1-methyl-3-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]tetrahydropyrimidin-2(1H)-one(1391930-67-8)

Safety Data

• Hazardous Substances Data: 1391930-67-8(Hazardous Substances Data)

Upstream product

• 7226-23-5 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1391930-90-7 1-(4-methoxybenzyl)-3-methyltetrahydropyrimidin-2(1H)-one 

Relevant articles and documents

Rh-catalyzed borylation of N-adjacent C(sp3)-H bonds with a silica-supported triarylphosphine ligand

Direct C(sp3)-H borylation of amides, ureas, and 2-aminopyridine derivatives at the position α to the N atom, which gives the corresponding α-aminoalkylboronates, has been achieved with a heterogeneous catalyst system consisting of [Rh(OMe)(cod)]2 and a silica-supported triarylphosphine ligand (Silica-TRIP) that features an immobilized triptycene-type cage structure with a bridgehead P atom. The reaction occurs not only at terminal C-H bonds but also at internal secondary C-H bonds under mild reaction conditions (25-100 °C, 0.1-0.5 mol % Rh).