1393381-99-1

Basic information

• Product Name: (R)-6-ethyl-4-phenyl-6-(trifluoromethyl)-5,6-dihydro-2H-pyran-2-one
• CAS NO: 1393381-99-1
• Molecular Weight: 270.251
• Mol File: 1393381-99-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-6-ethyl-4-phenyl-6-(trifluoromethyl)-5,6-dihydro-2H-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-6-ethyl-4-phenyl-6-(trifluoromethyl)-5,6-dihydro-2H-pyran-2-one(1393381-99-1)
• EPA Substance Registry System: (R)-6-ethyl-4-phenyl-6-(trifluoromethyl)-5,6-dihydro-2H-pyran-2-one(1393381-99-1)

Safety Data

• Hazardous Substances Data: 1393381-99-1(Hazardous Substances Data)

Upstream product

• 381-88-4 1,1,1-trifluoro-2-butanone 
• 98-86-2 acetophenone 
• 54976-37-3 3-phenylbut-2-en-1-ol 
• 1504-72-9 ethyl 3-phenylbut-2-enoate 
• 1196-67-4 3-phenyl-2-butenal 

Relevant articles and documents

Enantioselective vinylogous aldol/lactonization cascade reaction between β,γ-unsaturated amides and trifluoromethyl ketones: Facile access to chiral trifluoromethyl dihydropyranones

An efficient asymmetric vinylogous aldol/lactonization cascade reaction between β,γ-unsaturated amides and trifluoromethyl ketones has been developed. Using a chiral cyclohexanediamine-based tertiary amine-thiourea catalyst, optically active trifluoromethyl dihydropyranones have been constructed in moderate-to-excellent yields (up to 99%) with excellent stereoselectivities (96-> 99.5% ee). This journal is