1393642-98-2Relevant articles and documents
Studies to further investigate the inhibition of human liver microsomal CYP2C8 by the acyl-β-glucuronide of gemfibrozil
Jenkins, Susan M.,Zvyaga,Johnson,Hurley,Wagner,Burrell,Turley,Leet,Philip,Rodrigues
scheme or table, p. 2421 - 2430 (2012/03/26)
In previous studies, gemfibrozil acyl-β-glucuronide, but not gemfibrozil, was found to be a mechanism-based inhibitor of cytochrome P450 2C8. To better understand whether this inhibition is specific for gemfibrozil acyl-β-glucuronide or whether other gluc
