1394018-05-3 Usage
Description
(1-Aminocyclobutyl)(4-chlorophenyl)Methanone is a synthetic organic compound with the molecular formula C11H12ClNO. It features a cyclobutyl ring attached to a 4-chlorophenyl group and a methanone functional group. This versatile chemical serves as a building block in the synthesis of pharmaceuticals and bioactive compounds, and is also being studied for its potential pharmacological properties, such as analgesic and anti-inflammatory effects, as well as its possible application in treating neurological disorders.
Uses
Used in Pharmaceutical Synthesis:
(1-Aminocyclobutyl)(4-chlorophenyl)Methanone is used as a key intermediate in the synthesis of various pharmaceuticals and bioactive compounds. Its unique structure allows for the creation of a wide range of molecules with potential therapeutic applications.
Used in Medicinal Chemistry Research:
(1-AMinocyclobutyl)(4-chlorophenyl)Methanone is utilized in medicinal chemistry research as a starting point for developing new drugs with analgesic and anti-inflammatory properties. Its structure can be modified to explore different pharmacological activities and optimize its efficacy and safety.
Used in Neurological Disorder Treatment:
(1-Aminocyclobutyl)(4-chlorophenyl)Methanone is being investigated for its potential use in the treatment of neurological disorders. Its specific interactions with biological targets and mechanisms of action are being studied to determine its suitability as a therapeutic agent for such conditions.
Used in Drug Development:
In the drug development industry, (1-Aminocyclobutyl)(4-chlorophenyl)Methanone is used as a precursor in the design and synthesis of new chemical entities. Its unique structural features make it a valuable component in the creation of innovative medications with improved pharmacological profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 1394018-05-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,4,0,1 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1394018-05:
(9*1)+(8*3)+(7*9)+(6*4)+(5*0)+(4*1)+(3*8)+(2*0)+(1*5)=153
153 % 10 = 3
So 1394018-05-3 is a valid CAS Registry Number.
1394018-05-3Relevant articles and documents
N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor
Vallin, Karl S.A.,Sterky, Karin J.,Nyman, Eva,Bernstroem, Jenny,From, Rebecka,Linde, Christian,Minidis, Alexander B.E.,Nolting, Andreas,Naerhi, Katja,Santangelo, Ellen M.,Sehgelmeble, Fernando W.,Sohn, Daniel,Strindlund, Jennie,Weigelt, Dirk
supporting information; experimental part, p. 5485 - 5492 (2012/09/22)
A series of potent antagonists of the ion channel transient receptor potential A1 (TRPA1) was developed by modifying lead structure 16 that was discovered by high-throughput screening. Based on lead compound 16, a SAR was established, showing a narrow region at the nitro-aromatic R1 moiety and at the warhead, while the R2 side had a much wider scope including ureas and carbamates. Compound 16 inhibits Ca2+-activated TRPA1 currents reversibly in whole cell patch clamp experiments, indicating that under in vivo conditions, it does not react covalently, despite its potentially electrophilic ketone.
