1395087-42-9

Basic information

• Product Name: (Z)-3-(4-chloro-3-methylphenoxy)-3-phenylacrylonitrile
• Synonyms: (Z)-3-(4-chloro-3-methylphenoxy)-3-phenylacrylonitrile
• CAS NO: 1395087-42-9
• Molecular Weight: 269.73
• Mol File: 1395087-42-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-3-(4-chloro-3-methylphenoxy)-3-phenylacrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-(4-chloro-3-methylphenoxy)-3-phenylacrylonitrile(1395087-42-9)
• EPA Substance Registry System: (Z)-3-(4-chloro-3-methylphenoxy)-3-phenylacrylonitrile(1395087-42-9)

Safety Data

• Hazardous Substances Data: 1395087-42-9(Hazardous Substances Data)

Upstream product

• 59-50-7 4-Chloro-3-methylphenol 
• 935-02-4 3-Phenyl-2-propynonitrile 

Relevant articles and documents

Synthesis of (Z)-3-aryloxy-acrylonitriles, (E)-3-aryloxy-acrylonitriles and 3-cyanobenzofurans through the sequential reactions of phenols with propiolonitriles

A Na2CO3-promoted addition of phenols to propiolonitriles generated (Z)-3-aryloxy-acrylonitriles in nearly quantitative yields with exclusively Z-isomers, and a DABCO-promoted addition reaction of phenols with propiolonitriles afforded mainly (E)-3-aryloxy-acrylonitriles with high yields. The obtained (E)-3-aryloxy-acrylonitriles underwent intramolecular cyclization to give 3-cyanobenzofurans in good yields through palladium-catalyzed direct C-H bond functionalization.