1395171-42-2

Basic information

• Product Name: C₃₅H₅₁N₉O₃
• CAS NO: 1395171-42-2
• Molecular Weight: 645.848
• Mol File: 1395171-42-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₅H₅₁N₉O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₅H₅₁N₉O₃(1395171-42-2)
• EPA Substance Registry System: C₃₅H₅₁N₉O₃(1395171-42-2)

Safety Data

• Hazardous Substances Data: 1395171-42-2(Hazardous Substances Data)

Upstream product

• 5451-40-1 2,6 dichloropurine 
• 108-91-8 cyclohexylamine 
• 1246533-12-9 C₂₉H₃₉N₇O₄ 
• 69478-75-7 dimethyl-pyrrolidin-3-yl-amine 
• 1310346-84-9 methyl 1-[4-[[6-(cyclohexylamino)-9-tetrahydropyran-2-yl-purin-2-yl]amino]-3-methoxy-phenyl]piperidine-4-carboxylate 
• 39639-45-7 (2-chloro-9H-purin-6-yl)-cyclohexyl-amine 

Downstream Products

• 1383810-68-1 C₃₀H₄₃N₉O₂ 

Relevant articles and documents

Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors

Efforts to optimize biological activity, novelty, selectivity and oral bioavailability of Mps1 inhibitors, from a purine based lead MPI-0479605, are described in this Letter. Mps1 biochemical activity and cytotoxicity in HCT-116 cell line were improved. On-target activity confirmation via mechanism based G2/M escape assay was demonstrated. Physico-chemical and ADME properties were optimized to improve oral bioavailability in mouse.