139585-56-1

Basic information

• Product Name: 4-Chloro-2-(phenyl-trimethylsilanyloxy-methyl)-pyridine
• CAS NO: 139585-56-1
• Molecular Weight: 291.853
• Mol File: 139585-56-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Chloro-2-(phenyl-trimethylsilanyloxy-methyl)-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-(phenyl-trimethylsilanyloxy-methyl)-pyridine(139585-56-1)
• EPA Substance Registry System: 4-Chloro-2-(phenyl-trimethylsilanyloxy-methyl)-pyridine(139585-56-1)

Safety Data

• Hazardous Substances Data: 139585-56-1(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 139585-50-5 4-chloro-2-trimethylsilylpyridine 

Relevant articles and documents

On the Mechanism of the Carbodesilylation of 4- or 5-Substituted 2-(Trimethylsilyl)pyridines

An "ylide mechanism" is proposed for the carbodesilylation of 2-(trimethylsilyl)pyridines with benzaldehyde.In contrast, 3- and 4-(trimethylsilyl)pyridines, react only in the presence of a base catalyst via pyridyl anions with electrophiles.The rates of the uncatalyzed carbodesilylation reactions of 4-substituted 2-(trimethylsilyl)pyridines 2 with benzaldehyde correlate very well with the resonance parameters of the substituents ?0R, whereas the rates of 5-substituted 2-(trimethylsilyl)pyridines 7 correlate with the inductive substituent parameters ?1 in the Taft equation.This is to our knowledge the first direct determination of the resonance parameters ?0R.Key Words: Pyridines, substituted 2-(trimethylsilyl)-, synthesis of, carbodesilylation of / Carbodesilylation / Rate constants