1397684-99-9Relevant articles and documents
Selective esterifications of primary alcohols in a water-containing solvent
Wang, Yong,Aleiwi, Bilal A.,Wang, Qinghui,Kurosu, Michio
supporting information, p. 4910 - 4913,4 (2012/12/12)
Oxyma and an oxyma derivative, (2,2-dimethyl-1,3-dioxolan-4-yl)methyl 2-cyano-2-(hydroxyimino)acetate (5b), displayed a remarkable effect on selective esterifications of primary alcohols. A wide range of carboxylic acids could be esterified with primary alcohols by using EDCI, NaHCO3, and Oxyma or Oxyma derivative 5b in 5% H2O-CH3CN. Oxyma derivative 5b is particularly useful, since it could be removed after the reaction via a simple basic or an acidic aqueous workup procedure.