13981-56-1 Usage
Chemical Description
Hydrogen fluoride is a colorless gas or liquid used in the production of fluorine-containing compounds.
Chemical Properties
Colorless, fuming gas or liquid. Very
soluble in water. The liquid and gas consist of associated molecules. The vapor density corresponds
to hydrogen fluoride only at high temperatures.Nonflammable.
Uses
Catalyst in alkylation, isomerization, condensation, dehydration, and polymerization reactions;
fluorinating agent in organic and inorganic reactions; production of fluorine and aluminum fluoride; additive in liquid rocket propellants; refining
of uranium
Definition
ChEBI: The radioactive isotope of fluorine with relative atomic mass 18.000938. The longest-lived fluorine radionuclide with half-life of 109.77 min.
Hazard
Toxic by ingestion and inhalation, strong
irritant to eyes, skin, and mucous membranes.
Industrial uses
Hydrogen fluoride is the hydride of fluorine and the first member of the family of halogen acids. Anhydrous hydrogen fluoride is a mobile, colorless liquid that fumes strongly in air. Anhydrous hydrogen fluoride is an extremely powerful acid, exceeded in this respect only by 100% sulfuric acid. Like water, hydrogen fluoride is a liquid of high dielectric constant that undergoes self-ionization and forms conducting solutions with many solutes. Because anhydrous hydrogen fluoride is a superacid, many organic solutes dissolve in it to form stable carbonium ions. Hydrogen fluoride is a widely used industrial chemical. It was formerly used in the petroleum refining industry for the isomerization of aliphatic hydrocarbons to form more desirable automotive fuels, but this application has been superseded by other methods. The largest industrial use of hydrogen fluoride is in making fluorine- containing refrigerants (Freons, Genetrons). Another important use of hydrogen fluoride is in the preparation of organic fluorocarbon compounds by the Simons electrochemical process. In this procedure, an organic compound is dissolved in hydrogen fluoride, and an electric current is passed through the solution, whereupon the hydrogen atoms in the organic solute are replaced by fluorine. Hydrogen fluoride is employed in the electrochemical preparation of fluorine and for the preparation of inorganic fluorides. Thus, hydrogen fluoride is used for the conversion of uranium dioxide to uranium tetrafluoride, an intermediate in the preparation of uranium metal and uranium hexafluoride. With the great increase in nuclear energy-produced electricity, this represents an important use of hydrogen fluoride. Both hydrogen fluoride and hydrofluoric acid cause unusually severe burns; appropriate precautions must be taken to prevent any contact of the skin or eyes with either the liquid or the vapor.
Check Digit Verification of cas no
The CAS Registry Mumber 13981-56-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,8 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 13981-56:
(7*1)+(6*3)+(5*9)+(4*8)+(3*1)+(2*5)+(1*6)=121
121 % 10 = 1
So 13981-56-1 is a valid CAS Registry Number.
InChI:InChI=1/FH/h1H/i1-1
13981-56-1Relevant articles and documents
Dodgen, H. W.,Libby, W. F.
, p. 951 - 957 (1949)
Methyl Fluoride Formation from Thermal Fluorine-18 Reaction with Dimethylmercury
McKeown, F. P.,Iyer, Subramonia R.,Rowland, F. S.
, p. 3972 - 3975 (1983)
The attack of F on (CH3)2Hg with the formation of CH3F has been observed in the gas phase by using radioactive 18F atoms thermalized by multiple collisions in SF6.Approximately 9.6 +/- 1.0percent of thermal 18F atoms are found as CH318F by the
COX-2-targeted imaging agents
-
Page/Page column 25, (2008/06/13)
The presently disclosed subject matter provides a method for synthesizing a radiological imaging agent by reacting a COX-2-selective ligand with a compound comprising a detectable group, wherein the COX-2-selective ligand is a derivative of a non-steroidal anti-inflammatory drug (NSAID) comprising an ester moiety or a secondary amide moiety. Also provided are compositions that are synthesized using the method, as well as methods of using the compositions of the presently disclosed subject matter.
