13984-53-7 Usage
Description
METHYL 4-ACETYL-5-OXOHEXANOATE, a β-ketoester, is an organic compound with a molecular structure that features a ketone and an ester group. It is known for its role in various chemical reactions and synthetic processes, making it a valuable compound in the field of organic chemistry.
Uses
Used in Chemical Synthesis:
METHYL 4-ACETYL-5-OXOHEXANOATE is used as a synthetic intermediate for the preparation of various complex organic molecules. Its β-ketoester structure allows it to participate in a range of reactions, such as condensation and Michael addition reactions, which are crucial for the synthesis of target compounds.
Used in Modified Knorr Condensation:
In the field of heterocyclic chemistry, METHYL 4-ACETYL-5-OXOHEXANOATE is used as a reactant in modified Knorr condensation, a widely employed method for the synthesis of pyrroles. This reaction allows for the formation of diverse pyrrole derivatives, which are important in pharmaceuticals, agrochemicals, and materials science.
Used in the Synthesis of Dibenzyl-3,6-Dimethylpyrazine-2,5-Dicarboxylate:
METHYL 4-ACETYL-5-OXOHEXANOATE is also utilized in the preparation of dibenzyl-3,6-dimethylpyrazine-2,5-dicarboxylate, a compound with potential applications in the fragrance and flavor industry. Its unique structure contributes to the formation of the desired product, showcasing its versatility in organic synthesis.
Used in Analytical Chemistry:
METHYL 4-ACETYL-5-OXOHEXANOATE can be employed as a reference compound in analytical chemistry, particularly in gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) techniques. Its distinct chemical properties and fragmentation patterns make it useful for identifying and characterizing the Michael addition product in various reaction systems.
Check Digit Verification of cas no
The CAS Registry Mumber 13984-53-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,8 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13984-53:
(7*1)+(6*3)+(5*9)+(4*8)+(3*4)+(2*5)+(1*3)=127
127 % 10 = 7
So 13984-53-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H14O4/c1-6(10)8(7(2)11)4-5-9(12)13-3/h10H,4-5H2,1-3H3/b8-6+
13984-53-7Relevant articles and documents
Preparation method of delta-caprolactone
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Paragraph 0064; 0083-0084; 0086-0087; 0089-0092, (2021/08/25)
The invention relates to a preparation method of delta-caprolactone. The method comprises the following steps: dissolving a beta-dicarbonyl compound and a basic catalyst in a solvent, and conducting preheating; dropwise adding alkyl acrylate into a reaction system for a Michael addition reaction; cooling the system, adding alkali, and then heating the reaction system for saponification reaction; adding water, cooling the system, and adding a reducing agent for reaction; and cooling the system, adjusting the pH value with acid, and carrying out post-treatment to obtain the delta-caprolactone. The method disclosed by the invention is simple in process operation, high in safety, high in raw material utilization rate, short in total consumed time and free of generation of carbon dioxide.
Design and synthesis of high affinity inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferases directed by ligand efficiency dependent lipophilicity (LELP)
Rackham, Mark D.,Brannigan, James A.,Rangachari, Kaveri,Meister, Stephan,Wilkinson, Anthony J.,Holder, Anthony A.,Leatherbarrow, Robin J.,Tate, Edward W.
supporting information, p. 2773 - 2788 (2014/04/17)
N-Myristoyltransferase (NMT) is an essential eukaryotic enzyme and an attractive drug target in parasitic infections such as malaria. We have previously reported that 2-(3-(piperidin-4-yloxy)benzo[b]thiophen-2-yl)-5-((1,3, 5-trimethyl-1H-pyrazol-4-yl)meth
Poly(N-vinylimidazole) as efficient recyclable catalyst for the Michael addition of CH-acids to electron deficient alkenes in water
Tarasenko, E. A.,Beletskaya, I. P.,Tyurin, V. S.,Lamaty, F.
, p. 2613 - 2616,4 (2020/09/16)
Efficiency of poly(N-vinylimidazole) as the basic recyclable catalyst for the Michael addition of CH-acids to acrylonitrile, methyl acrylate, methyl vinyl ketone and methyl vinyl sulfone in water at ambient temperature was studied. In these reactions, formation of both 1 : 1 and 1 : 2 adducts is possible.