14068-01-0

Basic information

• Product Name: Benzamide, 4-chloro-N-[(4-methylphenyl)sulfonyl]-
• CAS NO: 14068-01-0
• Molecular Formula: C14H12ClNO3S
• Molecular Weight: 309.773
• Mol File: 14068-01-0.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzamide, 4-chloro-N-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-chloro-N-[(4-methylphenyl)sulfonyl]-(14068-01-0)
• EPA Substance Registry System: Benzamide, 4-chloro-N-[(4-methylphenyl)sulfonyl]-(14068-01-0)

Safety Data

• Hazardous Substances Data: 14068-01-0(Hazardous Substances Data)

Upstream product

• 4083-64-1 Tosyl isocyanate 
• 108-90-7 chlorobenzene 
• 104-88-1 4-chlorobenzaldehyde 
• 7335-27-5 ethyl 4-chlorobenzoate 
• 70-55-3 toluene-4-sulfonamide 
• 21849-40-1 dibromamine-T 
• 127-65-1 chloroamine-T 
• 941-55-9 4-toluenesulfonyl azide 
• 74-11-3 para-chlorobenzoic acid 
• 1576-37-0 N-benzyl-p-toluenesulfonamide 
• 5468-33-7 1-(4-chlorophenyl)-2-nitroethan-1-one 
• 92755-81-2 N-bromo-p-toluenesulfonamide 
• 106-39-8 bromochlorobenzene 
• 13939-06-5 molybdenum hexacarbonyl 

Relevant articles and documents

Chemoselective Cleavage of Acylsulfonamides and Sulfonamides by Aluminum Halides

The chemoselective cleavage of C-N bonds of amides, sulfonamides, and acylsulfonamides by aluminum halides is described. AlCl3and AlI3display complementary reactivities toward N-alkyl and N-acyl moieties. N-Alkylacylsulfonamides, sec

Metal-free C-H Activation over Graphene Oxide toward Direct Syntheses of Structurally Different Amines and Amides in Water

Unprecedented metal-free synthesis of a variety of amines and amides is reported via amination of C(sp3)-H and C(sp2)-H bonds. The strategy involves graphene-oxide/I2-catalyzed nitrene insertion using PhINTs as a nitrene (NT) source in water at room temperature. A wide range of structurally different substrates, viz., cyclohexane, cyclic ethers, arenes, alkyl aromatic systems, and aldehydes/ketones, having an α-phenyl ring have been employed successfully to afford the corresponding nitrene insertion product in good yield, albeit low in few cases. The envisaged method has superiority over others in terms of its operational simplicity, metal-free catalysis, use of water as a solvent, ambient reaction conditions, and reusability of the catalyst.

Efficient synthesis of carbon-11 labelled acylsulfonamides using [11C]CO carbonylation chemistry

Herein, a novel method for carbon-11 labeling of acyl sulfonamides by a one-step insertive [11C]CO carbonylative cross-coupling reaction between aryl halides and sulfonamides is presented. Various model compounds as well as drug molecules LY573636 (tasisulam) and ABT-199 were obtained in excellent yields. This method provides a valuable and widely applicable contribution to the continuously expanding radiochemical toolbox for PET research.