14093-86-8

Basic information

• Product Name: Naphthalene, 1-methoxy-2-methyl- (6CI,7CI,8CI,9CI)
• Synonyms: Naphthalene, 1-methoxy-2-methyl- (6CI,7CI,8CI,9CI)
• CAS NO: 14093-86-8
• Molecular Formula: C₁₂H₁₂O
• Molecular Weight: 172.22308
• Product Categories: NAPHTALENE
• Mol File: 14093-86-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Naphthalene, 1-methoxy-2-methyl- (6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 1-methoxy-2-methyl- (6CI,7CI,8CI,9CI)(14093-86-8)
• EPA Substance Registry System: Naphthalene, 1-methoxy-2-methyl- (6CI,7CI,8CI,9CI)(14093-86-8)

Safety Data

• Hazardous Substances Data: 14093-86-8(Hazardous Substances Data)

Usage

General Description

1-Methoxy-2-methyl-naphthalene is a chemical compound with the molecular formula C11H12O. It is a white solid substance that is insoluble in water and has a strong, sweet odor. This chemical is commonly used as a flavoring agent in foods and beverages, as well as in the production of fragrances and perfumes. It is also used as a precursor in the synthesis of other organic compounds. However, it is important to note that 1-methoxy-2-methyl-naphthalene may pose health risks if inhaled or ingested, and proper safety precautions should be observed when working with this chemical.

Upstream product

• 36336-08-0 methyl hypofluorite 
• 91-57-6 2-Methylnaphthalene 
• 67-56-1 methanol 
• 90-15-3 α-naphthol 
• 2216-69-5 1-Methoxynaphthalene 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 7469-77-4 2-methylnaphthalen-1-ol 

Downstream Products

• 59340-15-7 1-Acetoxy-4-benzyl-2-methyl-naphthalin 
• 59340-14-6 4-Benzyl-1-methoxy-2-methylnaphthalin 
• 56381-60-3 4-Benzyl-2-methyl-1-naphthol 
• 59340-13-5 4-Benzoyl-1-methoxi-2-methyl-naphthalin 
• 58-27-5 menadione 

Relevant articles and documents

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NMR and calculational studies on the regioselective lithiation of 1-methoxynaphthalene

1-Methoxynaphthalene (1) undergoes regioselective lithiation in position 2 (n-BuLi/TMEDA) or in position 8 (t-BuLi), respectively. The detected formation of a n-BuLi/1 complex (1:1 n-BuLi/1 mixture) appears to have only minor influence on the regioselectivity (both products are obtained). The exchange of hydrogen atom H2 by deuterium results in a remarkably reduced reaction rate for the lithiation with n-BuLi in THF-d8. This isotope effect and the formation of the thermodynamically less favorable 2-lithio compound suggest a kinetically controlled mechanism. The lack of an isotope effect for the reaction of 8-deuterio-1-methoxynaphthalene with t-BuLi and the formation of the thermodynamically preferred 8-lithiated product indicate a thermodynamically controlled mechanism. Slow conversion of the 2- into the 8-lithiated species (at higher temperatures) gives further evidence that n-BuLi and t-BuLi afford the kinetically and thermodynamically preferred products, respectively.

Functionalization of Aromatic Molecules Using HOF*CH3CN and CH3OF

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