1411627-73-0Relevant articles and documents
Selective cross-coupling of organic halides with allylic acetates
Anka-Lufford, Lukiana L.,Prinsell, Michael R.,Weix, Daniel J.
supporting information, p. 9989 - 10000 (2013/01/15)
A general protocol for the coupling of haloarenes with a variety of allylic acetates is presented. Strengths of the method are a tolerance for electrophilic (ketone, aldehyde) and acidic (sulfonamide, trifluoroacetamide) substrates and the ability to couple with a variety of substituted allylic acetates. Secondary alkyl bromides can also be allylated under slightly modified conditions, demonstrating the generality of the approach. Finally, the coupling of a reactive vinyl halide could be achieved by the use of a very hindered ligand and more reactive, branched allylic acetates.