141367-35-3

Basic information

• Product Name: 2-(2,5-dimethoxyphenyl)-2-trimethylsilyloxyacetonitrile
• Synonyms: 2-(2,5-dimethoxyphenyl)-2-trimethylsilyloxyacetonitrile
• CAS NO: 141367-35-3
• Molecular Weight: 265.384
• Mol File: 141367-35-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-(2,5-dimethoxyphenyl)-2-trimethylsilyloxyacetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,5-dimethoxyphenyl)-2-trimethylsilyloxyacetonitrile(141367-35-3)
• EPA Substance Registry System: 2-(2,5-dimethoxyphenyl)-2-trimethylsilyloxyacetonitrile(141367-35-3)

Safety Data

• Hazardous Substances Data: 141367-35-3(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 93-02-7 2,5-dimethoxybenzaldehyde 

Downstream Products

• 56979-58-9 2-(2,5-dimethoxyphenyl)-2-hydroxyacetonitrile 
• 60407-53-6 1-(2',5'-dimethoxyphenyl)-2-aminoethanol hydrochloride 
• 141381-40-0 N,N'-bis<2-hydroxy-2-(2,5-dimethoxyphenyl)ethyl>-hexamethylenediamine 
• 141367-31-9 N,N'-bis<2-hydroxy-2-(2,5-dimethoxyphenyl)ethyl>-tetramethylenediamine 
• 141367-37-5 5,5'-bis(2,5-dimethoxyphenyl)-3,3'-hexamethylenedi(oxazolidin-2-one) 
• 141367-38-6 5,5'-bis(2,5-dimethoxyphenyl)-3,3'-tetramethylenedi(oxazolidin-2-one) 
• 141367-36-4 5-(2,5-dimethoxyphenyl)oxazolidin-2-one 
• 100947-36-2 5-(2,5-Dimethoxy-phenyl)-oxazolidine-2,4-dione 
• 3600-87-1 desglymidodrine 

Relevant articles and documents

Solvent-free cyanosilylation of aromatic and heteroaryl aldehydes catalyzed by a cationic iron N-heterocyclic carbene complex at ambient temperature under UV irradiation

The cyanosilylation of aromatic aldehydes and heteroaryl aldehydes with trimethylsilyl cyanide (TMSCN) is efficiently catalyzed by an iron complex of the type {[3-isopropyl-1-(1R-phenylethyl)imidazol-2-ylidene]Fe(CO)2}I (3) in presence of UV li

Asymmetric synthesis of both enantiomers of 2-(dimethylamino)-1-[3-methoxy-2-(1-methyletyhoxy)phenyl]ethanol

Both enantiomers of 2-(dimethylamino)-1-[3- methoxy-2-(1-methylethoxy)phenyl]ethanol were synthetized by a stereoselective route and evaluated in vitro for their uroselectivity in comparison with other α1-adrenoceptor agonists. The most potent enantiomer was structurally characterized by X-ray crystallographic analysis.

Synthesis and adrenergic properties of new duplicated analogs of methoxamine

New duplicated analogs of the α1-selective agonist methoxamine and of its cyclic derivative 5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthylamine have been synthesized and tested for their adrenergic properties. All the compounds prepared, presenting a polymethylene spacer of varying length between two units of the active structure, turned out to be completely devoid of any α-stimulating activity. Surprisingly, some of them showed a marked β-adrenergic agonistic effect, being the most interesting compound active at nanomolar concentration.