141428-47-9

Basic information

• Product Name: 2-(2,3-Difluoro-6-nitrophenyl)acetic acid
• Synonyms: 2-(2,3-Difluoro-6-nitrophenyl)acetic acid;(2,3-Difluoro-6-nitrophenyl)acetic acid;2,3-Difluoro-6-nitrobenzeneacetic acid;Benzeneacetic acid, 2,3-difluoro-6-nitro-
• CAS NO: 141428-47-9
• Molecular Formula: C₈H₅F₂NO₄
• Molecular Weight: 217.13
• Mol File: 141428-47-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 154.0 to 158.0 °C
• Boiling Point: 345.138 °C at 760 mmHg
• Flash Point: 162.534 °C
• Appearance: /
• Density: 1.583 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: 2-8°C
• Solubility: slightly sol. in Methanol
• CAS DataBase Reference: 2-(2,3-Difluoro-6-nitrophenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,3-Difluoro-6-nitrophenyl)acetic acid(141428-47-9)
• EPA Substance Registry System: 2-(2,3-Difluoro-6-nitrophenyl)acetic acid(141428-47-9)

Safety Data

• Hazardous Substances Data: 141428-47-9(Hazardous Substances Data)

Usage

General Description

2-(2,3-Difluoro-6-nitrophenyl)acetic acid is a chemical compound with a specific molecular structure. It includes two fluorine atoms, one nitro group and a carboxylic acid group, which are attached to a phenyl ring. The presence of these entities can give the molecule specific chemical properties, such as acidity, reactivity, and potential interactions with other molecules. This chemical compound can be used in various chemical reactions or as a building block to synthesize more complex molecules in pharmaceutical or chemical research. Furthermore, like other chemical substances, it must be handled with care following the specified safety measures.

InChI:InChI=1/C8H5F2NO4/c9-5-1-2-6(11(14)15)4(8(5)10)3-7(12)13/h1-2H,3H2,(H,12,13)

Upstream product

• 145689-41-4 2-(2,3-difluorophenyl)acetic acid 
• 932373-69-8 diethyl 2-(2,3-difluoro-4-nitrophenyl)malonate 
• 996-82-7 sodium diethylmalonate 
• 771-69-7 2,3,4-trifluoronitrobenzene 

Downstream Products

• 141449-81-2 3,4-difluoro-2-(2-hydroxyethyl)nitrobenzene 
• 932373-72-3 2,3-difluoro-4-nitrotoluene 
• 914348-35-9 1,2-difluoro-3-methyl-4-nitrobenzene 

Relevant articles and documents

COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE

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2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors

2-(2-Chloro-6-fluorophenyl)acetamides having 2,2-difluoro-2-aryl/heteroaryl-ethylamine P3 and oxyguanidine P1 substituents are potent thrombin inhibitors (Ki = 0.9-33.9 nM). 2-(5-Chloro-pyridin-2-yl)-2,2-difluoroethylamine was the best P3 subst

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