141433-60-5 Usage
Description
This alkaloid occurs together with Neprotine (q.v.) in Berberis insignis Hook, B.
umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.).
It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.)
and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p.
265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p.
213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.).
Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the
ethylimide, m.p. 90°C.
Uses
Primarily for the treatment of gastroenteritis, dysentery and other intestinal infections and conjunctivitis, purulent otitis media.
References
Orekhov.,J. Amer. Pharm. Assoc., 30,247, (1941)
Chatterjee., ibid, 33,205,210 (1944)
Check Digit Verification of cas no
The CAS Registry Mumber 141433-60-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,4,3 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 141433-60:
(8*1)+(7*4)+(6*1)+(5*4)+(4*3)+(3*3)+(2*6)+(1*0)=95
95 % 10 = 5
So 141433-60-5 is a valid CAS Registry Number.
InChI:InChI=1/C20H18NO4.ClH.H2O/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;;/h3-4,7-10H,5-6,11H2,1-2H3;1H;1H2/q+1;;/p-1
