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1415-73-2

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1415-73-2 Usage

Chemical Properties

lemon yellow crystalline powder

Uses

Different sources of media describe the Uses of 1415-73-2 differently. You can refer to the following data:
1. Aloin is a naturally occurring substance found in various Aloe plant species. Aloin was originally used as a laxative in the treatment of constipation. Recent studies have investigated Aloin as an ant ineoplastic agent that enhances melanogenesis and transglutaminase activity.
2. Aloe exudant, used as a stimulant-laxative

Definition

ChEBI: A C-glycosyl compound that is beta-D-glucopyranose in which the anomeric hydroxy group is replaced by a 4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl moiety (the 9S d astereoisomer).

Safety Profile

Poison by subcutaneous andintravenous routes. Moderately toxic by ingestion. Whenheated to decomposition it emits acrid smoke and fumes.A carthartic and purgative.

Purification Methods

Aloin forms the monohydrate as lemon yellow crystals on crystallisation from H2O (450g/1.5L) which has a lower m ~70-80o than the anhydrous substance. [Cahn & Simonsen J Chem Soc 2573 1932, Hay & Haynes J Chem Soc 3141 1956.]

Check Digit Verification of cas no

The CAS Registry Mumber 1415-73-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,1 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1415-73:
(6*1)+(5*4)+(4*1)+(3*5)+(2*7)+(1*3)=62
62 % 10 = 2
So 1415-73-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H22O9/c22-6-8-4-10-14(21-20(29)19(28)17(26)13(7-23)30-21)9-2-1-3-11(24)15(9)18(27)16(10)12(25)5-8/h1-5,13-14,17,19-26,28-29H,6-7H2/t13-,14?,17-,19+,20-,21+/m1/s1

1415-73-2 Well-known Company Product Price

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  • USP

  • (1013727)  Aloin  United States Pharmacopeia (USP) Reference Standard

  • 1415-73-2

  • 1013727-25MG

  • 4,647.24CNY

  • Detail
  • Sigma-Aldrich

  • (50292)  Aloin  analytical standard

  • 1415-73-2

  • 50292-10MG

  • 5,093.01CNY

  • Detail

1415-73-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name aloin A

1.2 Other means of identification

Product number -
Other names 10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1415-73-2 SDS

1415-73-2Related news

Ultrasonic-Assisted Extraction of Aloin (cas 1415-73-2) from Aloe Vera Gel☆09/29/2019

Ultrasound assisted extraction (UAE) intensifies the kinetic of the extraction process by acting upon the interfacial area, through the disintegration of particles. Compared with batch extraction, it improves the extraction process decreasing both extraction time and temperature while increasing...detailed

Full length articleRole of Aloin (cas 1415-73-2) in the modulation of certain immune parameters in skin mucus of an Indian major carp, Labeo rohita09/28/2019

Enhancement of immune system seems to be the most promising method of preventing fish diseases. Several herbal products have immunostimulant properties, and are environmental friendly, economical and can act against a broad spectrum of pathogens. Present study was designed with an aim to evaluat...detailed

Aloin (cas 1415-73-2) attenuates cognitive impairment and inflammation induced by d-galactose via down-regulating ERK, p38 and NF-κB signaling pathway10/01/2019

Oxidative stress is considered as major culprit for neurodegenerative diseases and triggers cognitive and memory impairments. The present study mainly aimed to study the protective effects and underlying mechanisms of aloin on d-galactose (d-gal) induced ageing mice. Our results demonstrated tha...detailed

Evaluation of efficacy of Aloin (cas 1415-73-2) in treating acute trauma in vitro and in vivo09/27/2019

Clinical multiple acute trauma has brought great suffering for patients. The use of traditional Chinese medicine provides a new approach to treating trauma. Aloe Vera gel has been used to treat skin diseases for a long time, but its efficacy is not stable. As the most important part of the organ...detailed

Aloin (cas 1415-73-2) reduces inflammatory gene iNOS via inhibition activity and p-STAT-1 and NF-κB09/26/2019

Aloin is the major anthraquinone glycoside obtained from the Aloe species and exhibits anti-inflammatory and anti-oxidative activities. Here, we aimed to determine the effects of aloin on heme oxygenase-1 (HO-1) induction and on the expressions of inducible nitric oxide synthase (iNOS) and cyclo...detailed

Original ArticleEffect of Aloin (cas 1415-73-2) on viral neuraminidase and hemagglutinin-specific T cell immunity in acute influenza09/25/2019

Background: Millions of people are infected by the influenza virus worldwide every year. Current selections of anti-influenza agents are limited and their effectiveness and drug resistance are still of concern.Purpose: Investigation on in vitro and in vivo effect of aloin from Aloe vera leaves a...detailed

Renal protective effects of Aloin (cas 1415-73-2) in a mouse model of sepsis09/24/2019

Aloin is the major anthraquinone glycoside obtained from the Aloe species and exhibits anti-inflammatory and anti-oxidative activities. However, the renal protective effects of aloin and underlying molecular mechanism remain unclear. This study was initiated to determine whether aloin could modu...detailed

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