1415413-47-6

Basic information

• Product Name: (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(1-isobutyl-3-methylbutyl)-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxamide
• Synonyms: (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(1-isobutyl-3-methylbutyl)-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxamide
• CAS NO: 1415413-47-6
• Molecular Weight: 676.277
• Mol File: 1415413-47-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(1-isobutyl-3-methylbutyl)-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(1-isobutyl-3-methylbutyl)-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxamide(1415413-47-6)
• EPA Substance Registry System: (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(1-isobutyl-3-methylbutyl)-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxamide(1415413-47-6)

Safety Data

• Hazardous Substances Data: 1415413-47-6(Hazardous Substances Data)

Upstream product

• 534572-20-8 (3S,5R)-1-(tert-butoxycarbonyl)-3-(methoxycarbonyl)piperidine-5-carboxylic acid 
• 1415413-38-5 C₁₆H₂₆N₂O₆ 
• 1415413-39-6 C₁₇H₂₁N₃O₈S 
• 1415413-37-4 C₁₃H₁₇N₃O₆S 
• 1263197-94-9 C₁₉H₂₉N₃O₈S 
• 1263197-99-4 C₁₆H₂₁N₃O₇S 
• 1263197-96-1 methyl (3S,5R)-5-[(1,1-dimethyl-2-oxoethyl)amino]-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxylate 
• 1263198-01-1 methyl (3S,5R)-5-{[2-(2-chloroanilino)-1,1-dimethylethyl]amino}-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxylate 
• 1263198-04-4 methyl (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxylate 
• 65530-92-9 4-amino-2,6-dimethylheptane 
• 1263198-07-7 (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxylic acid 
• 944141-60-0 3-methyl (3R,5S)-5-[(1-isobutyl-3-methylbutyl)carbamoyl]piperidine-1,3-dicarboxylate 
• 1448902-64-4 methyl (3R,5S)-5-[(1-isobutyl-3-methylbutyl)carbamoyl]-1-(2-nitrophenyl)sulfonylpiperidine-3-carboxylate 
• 1448902-65-5 2-trimethylsilylethyl N-{(3R,5S)-5-[(1-isobutyl-3-methylbutyl)carbamoyl]-1-(2-nitrophenyl)sulfonyl-3-piperidyl}carbamate 

Downstream Products

• 1415413-22-7 C₂₇H₄₃ClN₄O₂ 

Relevant articles and documents

Synthesis and optimization of novel (3S,5R)-5-(2,2-dimethyl-5-oxo-4- phenylpiperazin-1-yl)piperidine-3-carboxamides as orally active renin inhibitors

We report synthesis and optimization of a series of (3S,5R)-5-(2,2- dimethyl-5-oxo-4-phenylpiperazin-1-yl)piperidine-3-carboxamides as renin inhibitors. Chemical modification of P1, P2 and P 3 portions led to a promising 3