1415963-60-8 Usage
Description
Oseltamivir Acid Hydrochloride, also known as Oseltamivir, is an orally active inhibitor of the influenza virus neuraminidase. It is a metabolite of Oseltamivir (O701000) and is converted in vivo to the active acid metabolite. This antiviral drug has been a focus of research in the context of COVID-19.
Uses
Used in Pharmaceutical Industry:
Oseltamivir Acid Hydrochloride is used as an antiviral agent for the treatment of influenza A and B infections. It works by inhibiting the neuraminidase enzyme, which is essential for the replication and transmission of the influenza virus. This helps to reduce the severity and duration of flu symptoms.
Used in COVID-19 Research:
Oseltamivir Acid Hydrochloride is used as a research product for investigating its potential role in the treatment or prevention of COVID-19. While it is primarily known for its effectiveness against influenza, researchers are exploring its possible applications in the context of the novel coronavirus due to its antiviral properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1415963-60-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,1,5,9,6 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1415963-60:
(9*1)+(8*4)+(7*1)+(6*5)+(5*9)+(4*6)+(3*3)+(2*6)+(1*0)=168
168 % 10 = 8
So 1415963-60-8 is a valid CAS Registry Number.
1415963-60-8Relevant articles and documents
Discovery of a series of novel compounds with moderate anti-avian H5N1 influenza virus activity in chick embryo
Xie, Yuanchao,Huang, Bing,Yu, Kexiang,Shi, Fangyuan,Xu, Wenfang
, p. 3485 - 3496 (2013/07/19)
Enlightened by some flavonoid compounds, which had been found as influenza neuraminidase inhibitors, we designed and synthesized a series of novel compounds containing different amino acid fragments. We also reported a simple synthetic route from oseltamivir to prepare its active form which was used as the positive control. The result of enzyme inhibition assay indicated that all the designed compounds displayed weak inhibitory activity against neuraminidase. However, they showed moderate anti-avian H5N1 influenza virus activity in chick embryo. Besides interfering with the function of neuraminidase, these compounds seemed to inhibit the replication of influenza virus by some other mechanism which deserved deep study.
