1416008-35-9

Basic information

• Product Name: tert-butyl 4'-tert-butyl-5'-(2,6-dichlorophenyl)-2-oxo-2'-phenyl-2',4'-dihydrospiro[indoline-3,3'-pyrazole]-1-carboxylate
• Synonyms: tert-butyl 4'-tert-butyl-5'-(2,6-dichlorophenyl)-2-oxo-2'-phenyl-2',4'-dihydrospiro[indoline-3,3'-pyrazole]-1-carboxylate
• CAS NO: 1416008-35-9
• Molecular Weight: 564.511
• Mol File: 1416008-35-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 4'-tert-butyl-5'-(2,6-dichlorophenyl)-2-oxo-2'-phenyl-2',4'-dihydrospiro[indoline-3,3'-pyrazole]-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4'-tert-butyl-5'-(2,6-dichlorophenyl)-2-oxo-2'-phenyl-2',4'-dihydrospiro[indoline-3,3'-pyrazole]-1-carboxylate(1416008-35-9)
• EPA Substance Registry System: tert-butyl 4'-tert-butyl-5'-(2,6-dichlorophenyl)-2-oxo-2'-phenyl-2',4'-dihydrospiro[indoline-3,3'-pyrazole]-1-carboxylate(1416008-35-9)

Safety Data

• Hazardous Substances Data: 1416008-35-9(Hazardous Substances Data)

Upstream product

• 630-19-3 pivalaldehyde 
• 1416007-57-2 (E)-tert-butyl 3-(2,2-dimethylpropylidene)-2-oxoindoline-1-carboxylate 
• 39719-44-3 2,6-dichloro-N'-phenylbenzohydrazonoyl chloride 
• 6579-24-4 1-(2,6-dichlorobenzylidene)-2-phenylhydrazine 
• 58808-09-6 (E)-3-(2,2-dimethylpropylidene)indolin-2-one 
• 59-48-3 2-oxoindole 

Relevant articles and documents

Asymmetric catalytic 1,3-dipolar cycloaddition reaction of nitrile imines for the synthesis of chiral spiro-pyrazoline-oxindoles

A new 1,3-dipolar cycloaddition of nitrile imines with 3-alkenyl-oxindoles was catalyzed by a new chiral Mg(ClO4)2 complex of an N,N'-dioxide ligand. The reaction is so far the sole catalytic synthesis of spiro-pyrazoline-oxindole derivatives. A wide variety of substrates were explored to obtain good yields (up to 98%) and excellent enantioselectivities (up to 99%). This cycloaddition expands the scope of propargyl anion type 1,3-dipole in the construction of 2-pyrazoline subunit.