1416083-34-5Relevant articles and documents
Continuous Flow Synthesis of [Au(NHC)(Aryl)] (NHC=N-Heterocyclic Carbene) Complexes
Cauwenbergh, Thibault,Tzouras, Nikolaos V.,Scattolin, Thomas,Bhandary, Subhrajyoti,Simoens, Andreas,Van Hecke, Kristof,Stevens, Christian V.,Nolan, Steven P.
, p. 13342 - 13345 (2021)
The use of weak and inexpensive bases has recently opened promising perspectives towards the simpler and more sustainable synthesis of Au(I)-aryl complexes with valuable applications in catalysis, medicinal chemistry, and materials science. In recent years, continuous manufacturing has shown to be a reliable partner in establishing sustainable and controlled process scalability. Herein, the first continuous flow synthesis of a range of Au(I)-aryl starting from widely available boronic acids and various [Au(NHC)Cl] (NHC=N-heterocyclic carbene) complexes in unprecedentedly short reaction times and high yields is reported. Successful synthesis of previously non- or poorly accessible complexes exposed fascinating reactivity patterns. Via a gram-scale synthesis, convenient process scalability of the developed protocol was showcased.
The fluoride-free transmetalation of organosilanes to gold
Dupuy, Stéphanie,Slawin, Alexandra M. Z.,Nolan, Steven P.
supporting information, p. 14923 - 14928 (2013/01/15)
Golden transfer: The versatile gold(I) complex [Au(IPr)(OH)] permits very straightforward access to a series of aryl-, vinyl-and alkylgold silanolates by reaction with the appropriate silane reagent. These silanolate compounds are key intermediates in a f
