141685-13-4Relevant articles and documents
In vitro antifungal activity of new series of homoallylamines and related compounds with inhibitory properties of the synthesis of fungal cell wall polymers
Vargas M., Leonor Y.,Castelli, Maria V.,Kouznetsov, Vladimir V.,Urbina G., Juan M.,Lopez, Silvia N.,Sortino, Maximiliano,Enriz, Ricardo D.,Ribas, Juan C.,Zacchino, Susana
, p. 1531 - 1550 (2007/10/03)
The synthesis, in vitro antifungal evaluation and SAR studies of 101 compounds of the 4-aryl-, 4-alkyl-, 4-pyridyl or -quinolinyl-4-N-arylamino-1-butenes series and related compounds, are reported here. Active structures showed to inhibit (1,3)-β-D-glucan and mainly chitin synthases, enzymes that catalyze the synthesis of the major fungal cell wall polymers.
SYNTHESIS OF β-LACTAMS BY CONDENSATION OF TITANIUM ENOLATES OF 2-PYRIDYL THIOESTERS WITH AROMATIC IMINES: INFLUENCE OF THE PYRIDINE STRUCTURE ON THE DIASTEREOSELECTION
Annunziata, Rita,Cinquini, Mauro,Cozzi, Franco,Lombardi Borgia, Andrea
, p. 181 - 184 (2007/10/02)
A series or S-2-pyridyl thioesters featuring various substituent at the 3 or 6 position of the pyridine ring has been prepared and their titanium enolates have been reacted with imines to give β-lactams. 3-substituted compounds provided a good diastereose
