14171-89-2

Basic information

• Product Name: 6-PHENYL-HEXAN-2-ONE
• Synonyms: 6-PHENYL-HEXAN-2-ONE;1-Phenylhexane-5-one;6-Phenyl-2-hexanone;6-Phenylhexane-2-one
• CAS NO: 14171-89-2
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25484
• EINECS: 238-017-2
• Mol File: 14171-89-2.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 299.9 °C at 760 mmHg
• Flash Point: 145 °C
• Appearance: /
• Density: 0.95 g/cm³
• Vapor Pressure: 0.00116mmHg at 25°C
• Refractive Index: 1.498
• CAS DataBase Reference: 6-PHENYL-HEXAN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-PHENYL-HEXAN-2-ONE(14171-89-2)
• EPA Substance Registry System: 6-PHENYL-HEXAN-2-ONE(14171-89-2)

Safety Data

• Hazardous Substances Data: 14171-89-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O/c1-11(13)7-5-6-10-12-8-3-2-4-9-12/h2-4,8-9H,5-7,10H2,1H3

Upstream product

• 104-55-2 3-phenyl-propenal 
• 91368-25-1 6-phenylhex-3-en-5-yne-2-one 
• 4173-44-8 1-phenyl-1,3-hexadien-5-one 
• 98-80-6 phenylboronic acid 
• 104-53-0 3-phenyl-propionaldehyde 
• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 
• 10226-30-9 6-chloro-2-hexanone 
• 71-43-2 benzene 
• 34420-17-2 (2-phenylethyl)boronic acid 
• 78-94-4 methyl vinyl ketone 
• 60-12-8 2-phenylethanol 
• 4455-09-8 2-phenylethyl tosylate 
• 637-59-2 1-Bromo-3-phenylpropane 
• 33046-41-2 6-phenylhex-3-en-2-one 

Downstream Products

• 87657-69-0 (E)-1-(4-hydroxyphenyl)-7-phenylhept-1-en-3-one 
• 1443545-69-4 acetic acid (E)-2-acetoxy-4-(3-oxo-7-phenyl-hept-1-enyl)phenyl ester 
• 73948-23-9 4-hexylbenzene-1-sulfonyl chloride 
• 4619-85-6 4-hexylbenzenethiol 
• 1077-16-3 hexylbenzene 
• 54636-34-9 3,6-diphenyl-2-hexanone 
• 87657-66-7 (E)-1-(3-hydroxy-4-methoxyphenyl)-7-phenylhept-1-en-3-one 
• 99742-12-8 (E)-1,7-diphenylhept-1-en-3-one 
• 739304-38-2 1-methyl-5-phenyl-pentylamine 
• 2270-20-4 5-Phenylpentanoic acid 
• 768-56-9 4-Phenylbut-1-ene 
• 2046-18-6 4-phenylbutyronitrile 

Relevant articles and documents

Selective Decarbalkoxylation of β-Keto Esters

-

Chiral isoxazolidine-mediated stereoselective umpolung α-phenylation of methyl ketones

An effective asymmetric α-phenylation of methyl ketones with triphenylaluminium in the presence of (+)-benzopyranoisoxazolidine has been developed. The reaction proceeds via the in situ formation of a chiral N-alkoxyenamine and the subsequent diastereoselective nucleophilic phenylation to provide α-phenylated products in moderate to good yields, with high enantioselectivities.

Organic photocatalysis for the radical couplings of boronic acid derivatives in batch and flow

We report an acridium-based organic photocatalyst as an efficient replacement for iridium-based photocatalysts to oxidise boronic acid derivatives by a single electron process. Furthermore, we applied the developed catalytic system to the synthesis of four active pharmaceutical ingredients (APIs). A straightforward scale up approach using continuous flow photoreactors is also reported affording gram an hour throughput.