141743-64-8

Basic information

• Product Name: C-[(4-{3-[4-(Imino-piperidin-1-yl-methyl)-phenoxy]-propoxy}-phenyl)-piperidin-1-yl]-methyleneamine; hydrochloride
• CAS NO: 141743-64-8
• Molecular Weight: 521.53
• Mol File: 141743-64-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C-[(4-{3-[4-(Imino-piperidin-1-yl-methyl)-phenoxy]-propoxy}-phenyl)-piperidin-1-yl]-methyleneamine; hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: C-[(4-{3-[4-(Imino-piperidin-1-yl-methyl)-phenoxy]-propoxy}-phenyl)-piperidin-1-yl]-methyleneamine; hydrochloride(141743-64-8)
• EPA Substance Registry System: C-[(4-{3-[4-(Imino-piperidin-1-yl-methyl)-phenoxy]-propoxy}-phenyl)-piperidin-1-yl]-methyleneamine; hydrochloride(141743-64-8)

Safety Data

• Hazardous Substances Data: 141743-64-8(Hazardous Substances Data)

Upstream product

• 7476-06-4 1,3-bis(4-cyanophenoxy)propane 

Relevant articles and documents

N1-substituted benzamidines: Synthesis, antiproteinase activity and inhibition of tumor cell growth

We have synthesized N1-substituted benzamidines and polybenzamidines with the aim to produce antitumor drugs retaining differential biological properties with respect to unsubstituted compounds. Antiproliferative activity on in vitro cultured human leukemic cells was exhibited by N1-substituted polybenzamidines, while N1-substituted benzamidines were found to retain very low antitumor effects. Furthermore, our results suggest that N1-substituted benzamidines and some of polybenzamidines exhibit low activity on trypsin and kallikrein. Taken together these data indicate that some N1-substituted polybenzamidines could be of interest for experimental antitumor therapy, since are likey to retain low side effects due to alteration of proteinase activity.