1417888-93-7Relevant articles and documents
Synthesis of spiroindoline phytoalexin (S)-(-)-spirobrassinin and its unnatural (R)-(+)-enantiomer
Budovská, Mariana,Kutschy, Peter,Ko?ár, Tibor,Gondová, Ta?ána,Petrovaj, Ján
, p. 1092 - 1104 (2013/03/13)
The stereoselective syntheses of the cruciferous indole phytoalexin (S)-(-)-spirobrassinin and its unnatural (R)-(+)-enantiomer were achieved by bromine-induced spirocyclization of (-)- and (+)-1-(8-phenylmenthoxycarbonyl) brassinin in the presence of water to give the corresponding spirobrasinol derivatives, followed by oxidation to the derivatives of spirobrassinin and finally removal of the chiral auxiliary.
