1419874-04-6

Basic information

• Product Name: (S)-3-hydroxy-4-[(1-phenyltetrazole-5-yl)sulfanyl]butyronitrile
• Synonyms: (S)-3-hydroxy-4-[(1-phenyltetrazole-5-yl)sulfanyl]butyronitrile
• CAS NO: 1419874-04-6
• Molecular Weight: 261.307
• Mol File: 1419874-04-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-3-hydroxy-4-[(1-phenyltetrazole-5-yl)sulfanyl]butyronitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-hydroxy-4-[(1-phenyltetrazole-5-yl)sulfanyl]butyronitrile(1419874-04-6)
• EPA Substance Registry System: (S)-3-hydroxy-4-[(1-phenyltetrazole-5-yl)sulfanyl]butyronitrile(1419874-04-6)

Safety Data

• Hazardous Substances Data: 1419874-04-6(Hazardous Substances Data)

Upstream product

• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 127913-44-4 (S)-4-chloro-3-hydroxy butyronitrile 

Downstream Products

• 1419874-05-7 (S)-3-trimethylsiloxy-4-[(1-phenyltetrazole-5-yl)sulfanyl]butyronitrile 
• 1419874-06-8 tert-butyl (5S)-5-hydroxy-3-oxo-6-(1-phenyltetrazole-5-sulfanyl) hexanoate 
• 1419874-07-9 tert-butyl (3R,5S)-3,5-dihydroxy-6-(1-phenyltetrazole-5-sulfanyl)hexanoate 
• 380460-39-9 [(4R,6S)-2,2-dimethyl-6-(1-phenyl-1H-tetrazol-5-ylsulfanylmethyl)[1,3]dioxan-4-yl]acetic acid tert-butyl ester 
• 380460-37-7 [(4R,6S)-2,2-dimethyl-6-(1-phenyl-1H-tetrazole-5-sulfonylmethyl)[1,3]dioxan-4-yl]acetic acid tert-butyl ester 

Relevant articles and documents

INTERMEDIATE OF STATIN DRUGS AND PREPARATION THEREOF

The present invention relates to the field of pharmaceutical chemistry, specifically relates to a statin intermediate having formula I and preparation thereof. The advantages of the method used to prepare the chiral sulfone intermediate having formula I are that a fluorophore is introduced at the beginning of the synthesis, and the intermediates are mostly solid, which enables quality control to be easily carried out.