142-28-9

Basic information

• Product Name: 1,3-Dichloropropane
• Synonyms: 1,3-DICHLOROPROPANE;AKOS BBS-00004406;TRIMETHYLENE DICHLORIDE;TRIMETHYLENE CHLORIDE;1,3-dichloro-propan;1,3-Dichlorpropan;1,3-dichlroropropane;1,3-Propylenechloride
• CAS NO: 142-28-9
• Molecular Formula: C₃H₆Cl₂
• Molecular Weight: 112.99
• EINECS: 205-531-3
• Product Categories: alpha,omega-Bifunctional Alkanes;alpha,omega-Dichloroalkanes;Monofunctional & alpha,omega-Bifunctional Alkanes;Analytical Chemistry;Standard Solution of Volatile Organic Compounds for Water & Soil Analysis;Standard Solutions (VOC);Alpha Sort;D;DAlphabetic;DIA - DIC;Volatiles/ Semivolatiles
• Mol File: 142-28-9.mol
• Article Data: 24

Chemical Properties

• Melting Point: −99 °C(lit.)
• Boiling Point: 120-122 °C(lit.)
• Flash Point: 90 °F
• Appearance: Clear colorless/Liquid
• Density: 1.19 g/mL at 25 °C(lit.)
• Vapor Pressure: 18.3mmHg at 25°C
• Refractive Index: n20/D 1.448(lit.)
• Storage Temp.: Refrigerator
• Water Solubility: 0.8 g/L (20 ºC)
• BRN: 505960
• CAS DataBase Reference: 1,3-Dichloropropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dichloropropane(142-28-9)
• EPA Substance Registry System: 1,3-Dichloropropane(142-28-9)

Safety Data

• Hazard Codes: F,Xn,T,Xi
• Statements: 11-20-20/22-52/53-36/37/38-39/23/24/25-23/24/25-36-20/21/22
• Safety Statements: 9-16-29-33-24-61-26-45-36/37-7
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 2
• RTECS: TX9660000
• TSCA: Yes
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 142-28-9(Hazardous Substances Data)

Usage

Chemical Properties

1,3-Dichloropropene occurs as a clear colourless liquid with a sweet chloroform-like odor. It is soluble in alcohol and ether, dissolves in water (0.27g/100ml). The half-life of 1,3-dichloropropene in ambient air may range from 7 to 50 hours.

Uses

1,3-Dichloropropane is used as an intermediate in organic synthesis. It is also used as solvent, detergent and chromatographic analysis. Further, it is used to prepare 3,7-dithia-nonanedioic acid by reacting with mercaptoacetic acid.

Definition

ChEBI: 1,3-dichloropropane is a chloroalkane that is propane in which a hydrogen from each of the terminal methyl groups has been replaced by a chlorine. It has a role as an environmental contaminant and a nematicide. It is a chloroalkane and a chlorohydrocarbon.

Preparation

1,3-Dichloropropane is obtained by the action of propylene glycol with hydrochloric acid.1,3-Dichloropropane synthesis: A process for the preparation of 1,3-dichloropropane by reacting bis(3-hydroxypropyl)ether with hydrogen chloride, optionally in the presence of tertiary basic nitrogen compounds or other tertiary aliphatic bases as catalysts, distilling off the 1,3-dichloropropane and the water of reaction and working up the two phases. Process for the preparation of 1,3-dichloropropane

Synthesis Reference(s)

The Journal of Organic Chemistry, 29, p. 194, 1964 DOI: 10.1021/jo01024a045

General Description

1,3-dichloropropane is a colorless watery liquid with a sweet odor. Sinks in?water. Produces irritating vapor. (USCG, 1999)

Air & Water Reactions

Highly flammable.

Reactivity Profile

Halogenated aliphatic compounds, such as 1,3-Dichloropropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Health Hazard

INHALATION: May cause some central nervous system depression. EYES: May cause some pain and irritation. SKIN: Mild irritation.

Safety Profile

Moderately toxic by ingestion. Mutation data reported. A very dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits highly toxic fumes of Cl and phosgene. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and PROPYLENE DICHLORIDE.

InChI:InChI=1/C3H6Cl2/c4-2-1-3-5/h1-3H2

Synthetic route

trimethyleneglycol (504-63-2) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With hydrogenchloride; ammonium chloride In water at 60 - 107℃; for 3h;	97.2%
With hydrogenchloride at 80℃; for 48h;	10%
With thionyl chloride

cyclopropane (75-19-4) → cyclopropyl chloride (7393-45-5) + 1,1-dichlorocyclopropane (2088-35-9) + 1,3-Dichloropropane (142-28-9) + 3-chloroprop-1-ene (107-05-1)

Conditions	Yield
With chlorine; silicon tetrafluoride at 600℃; Product distribution; Irradiation;	A 83.5% B 4% C n/a D 2.6%

trimethyleneglycol (504-63-2) → 1,3-Dichloropropane (142-28-9) + 1-chloro-3-hydroxypropane (627-30-5)

Conditions	Yield
With tetrachloromethane; triphenylphosphine In acetonitrile Product distribution; Mechanism;	A 16% B 75%
With hydrogenchloride at 100℃;
With hydrogenchloride
With tert-butylhypochlorite; triphenylphosphine In chloroform Product distribution; 1.) -70 deg C, 2.) RT, 3.) reflux, 24 h;

cyclopropane (75-19-4) → 1,1,3-trichloropropane (20395-25-9) + 1,2,3-trichloropropane (96-18-4) + cyclopropyl chloride (7393-45-5) + 1,1-dichlorocyclopropane (2088-35-9) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With chlorine In trichlorofluoromethane at 21℃; for 0.0833333h; Product distribution; Mechanism; Irradiation; also 1,3-dichloropropane; var. solvents (also in the gas phase);	A 13% B 8.7% C 11% D 0.4% E 67%

trimethyleneglycol (504-63-2) → 1,3-Dichloropropane (142-28-9) + 2-chloro-1,3,2-dioxaphosphinane (6362-89-6) + 3-chloro-n-propyl-dichlorophosphite

Conditions	Yield
With phosphorus trichloride In dichloromethane for 2h; Ambient temperature;	A n/a B 48% C 5%

trimethylene oxide (503-30-0) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With phosphorus pentachloride

3-chloropropyl p-toluenesulfonate (632-02-0) + diethyl ether (60-29-7) + butylmagnesium chloride → 1,3-Dichloropropane (142-28-9)

formaldehyd (50-00-0) + ethene (74-85-1) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With hydrogenchloride at 149 - 154℃; under 540598 - 680345 Torr;

propane (74-98-6) → 1,2-Dichloropropane (26198-63-0, 78-87-5) + 2,2-dichloropropane (594-20-7) + 1,1-dichloropropane (78-99-9) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
at 400℃; Product distribution; thermische Chlorierung;
at 400℃; Product distribution; thermische Chlorierung;

ethene (74-85-1) + dichloromethane (75-09-2) → 1,5-dichloropentane (628-76-2) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With water; dibenzoyl peroxide at 200℃; under 55163.1 - 73550.8 Torr;

1-Chloropropane (540-54-5) → 1,2-Dichloropropane (26198-63-0, 78-87-5) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With sulfuryl dichloride; 1,2-dichloro-benzene; dibenzoyl peroxide
With sulfuryl dichloride; dilauryl peroxide; chlorobenzene
With sulfuryl dichloride; dilauryl peroxide; 1,2-dichloro-benzene

1,3-Diiodopropane (627-31-6) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With water; silver(I) chloride

benzyl chloride (100-44-7) + trimethyleneglycol (504-63-2) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With triphenyl phosphite at 170 - 180℃;

ethanol (64-17-5) + 1,3-chlorobromopropane (109-70-6) → 1,3-Dichloropropane (142-28-9) + 1,3-dibromo-propane (109-64-8)

1,3-dibromo-propane (109-64-8) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With antimonypentachloride
With mercury dichloride

1-chloro-3-hydroxypropane (627-30-5) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With thionyl chloride

phosgene (75-44-5) + 3-methoxypropylamine (5332-73-0) + 1-Chloronaphthalene (90-13-1) → 3-Chloropropyl isocyanate (13010-19-0) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
at 140 - 150℃; das Hydrochlorid reagiert;

1-Chloropropane (540-54-5) → 1,2-Dichloropropane (26198-63-0, 78-87-5) + 1,1-dichloropropane (78-99-9) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With chlorine In 1,2-dichloro-benzene at 0℃; Product distribution; oth. temperatures;
With N-chloropiperidine; 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 30℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;
With chlorine In benzene at -10.1℃; Product distribution; dependence of the selectivity of chlorination on the conc. of benzene;
With sulfuryl dichloride; dibenzoyl peroxide
With chlorine Ambient temperature; Irradiation;

1,1,3-trichloropropane (20395-25-9) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With triethylsilane; decacarbonyldirhenium(0) at 160℃; for 5h;	48 % Chromat.
With triethylsilane; Re(CO)10 at 159.9℃; for 5h; Rate constant; other catalyst, time, temperature;	20 % Chromat.

cyclopropane (75-19-4) → hydrogenchloride (7647-01-0) + cyclopropyl chloride (7393-45-5) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With chlorine at -263.2℃; Quantum yield; Irradiation; further temps.;

trimethyleneglycol (504-63-2) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With hydrogenchloride; ammonium chloride In water at 60 - 107℃; for 3h;	97.2%
With hydrogenchloride at 80℃; for 48h;	10%
With thionyl chloride

cyclopropane (75-19-4) → cyclopropyl chloride (7393-45-5) + 1,1-dichlorocyclopropane (2088-35-9) + 1,3-Dichloropropane (142-28-9) + 3-chloroprop-1-ene (107-05-1)

Conditions	Yield
With chlorine; silicon tetrafluoride at 600℃; Product distribution; Irradiation;	A 83.5% B 4% C n/a D 2.6%

trimethyleneglycol (504-63-2) → 1,3-Dichloropropane (142-28-9) + 1-chloro-3-hydroxypropane (627-30-5)

Conditions	Yield
With tetrachloromethane; triphenylphosphine In acetonitrile Product distribution; Mechanism;	A 16% B 75%
With hydrogenchloride at 100℃;
With hydrogenchloride
With tert-butylhypochlorite; triphenylphosphine In chloroform Product distribution; 1.) -70 deg C, 2.) RT, 3.) reflux, 24 h;

cyclopropane (75-19-4) → 1,1,3-trichloropropane (20395-25-9) + 1,2,3-trichloropropane (96-18-4) + cyclopropyl chloride (7393-45-5) + 1,1-dichlorocyclopropane (2088-35-9) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With chlorine In trichlorofluoromethane at 21℃; for 0.0833333h; Product distribution; Mechanism; Irradiation; also 1,3-dichloropropane; var. solvents (also in the gas phase);	A 13% B 8.7% C 11% D 0.4% E 67%

trimethyleneglycol (504-63-2) → 1,3-Dichloropropane (142-28-9) + 2-chloro-1,3,2-dioxaphosphinane (6362-89-6) + 3-chloro-n-propyl-dichlorophosphite

Conditions	Yield
With phosphorus trichloride In dichloromethane for 2h; Ambient temperature;	A n/a B 48% C 5%

trimethylene oxide (503-30-0) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With phosphorus pentachloride

3-chloropropyl p-toluenesulfonate (632-02-0) + diethyl ether (60-29-7) + butylmagnesium chloride → 1,3-Dichloropropane (142-28-9)

formaldehyd (50-00-0) + ethene (74-85-1) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With hydrogenchloride at 149 - 154℃; under 540598 - 680345 Torr;

propane (74-98-6) → 1,2-Dichloropropane (26198-63-0, 78-87-5) + 2,2-dichloropropane (594-20-7) + 1,1-dichloropropane (78-99-9) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
at 400℃; Product distribution; thermische Chlorierung;
at 400℃; Product distribution; thermische Chlorierung;

ethene (74-85-1) + dichloromethane (75-09-2) → 1,5-dichloropentane (628-76-2) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With water; dibenzoyl peroxide at 200℃; under 55163.1 - 73550.8 Torr;

1-Chloropropane (540-54-5) → 1,2-Dichloropropane (26198-63-0, 78-87-5) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With sulfuryl dichloride; 1,2-dichloro-benzene; dibenzoyl peroxide
With sulfuryl dichloride; dilauryl peroxide; chlorobenzene
With sulfuryl dichloride; dilauryl peroxide; 1,2-dichloro-benzene

1,3-Diiodopropane (627-31-6) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With water; silver(I) chloride

benzyl chloride (100-44-7) + trimethyleneglycol (504-63-2) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With triphenyl phosphite at 170 - 180℃;

ethanol (64-17-5) + 1,3-chlorobromopropane (109-70-6) → 1,3-Dichloropropane (142-28-9) + 1,3-dibromo-propane (109-64-8)

1,3-dibromo-propane (109-64-8) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With antimonypentachloride
With mercury dichloride

1-chloro-3-hydroxypropane (627-30-5) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With thionyl chloride

phosgene (75-44-5) + 3-methoxypropylamine (5332-73-0) + 1-Chloronaphthalene (90-13-1) → 3-Chloropropyl isocyanate (13010-19-0) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
at 140 - 150℃; das Hydrochlorid reagiert;

1-Chloropropane (540-54-5) → 1,2-Dichloropropane (26198-63-0, 78-87-5) + 1,1-dichloropropane (78-99-9) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With chlorine In 1,2-dichloro-benzene at 0℃; Product distribution; oth. temperatures;
With N-chloropiperidine; 2,2'-azobis(isobutyronitrile) In trifluoroacetic acid at 30℃; Product distribution; Rate constant; Irradiation; relative rate constants, position selectivity, substrate selectivity;
With chlorine In benzene at -10.1℃; Product distribution; dependence of the selectivity of chlorination on the conc. of benzene;
With sulfuryl dichloride; dibenzoyl peroxide
With chlorine Ambient temperature; Irradiation;

1,1,3-trichloropropane (20395-25-9) → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With triethylsilane; decacarbonyldirhenium(0) at 160℃; for 5h;	48 % Chromat.
With triethylsilane; Re(CO)10 at 159.9℃; for 5h; Rate constant; other catalyst, time, temperature;	20 % Chromat.

cyclopropane (75-19-4) → hydrogenchloride (7647-01-0) + cyclopropyl chloride (7393-45-5) + 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With chlorine at -263.2℃; Quantum yield; Irradiation; further temps.;

1,3-chlorobromopropane (109-70-6) → 1,2-Dichloropropane (26198-63-0, 78-87-5) + 1,2-Dibromopropane (78-75-1) + 1,3-Dichloropropane (142-28-9) + allyl bromide (106-95-6) + 1,3-dibromo-propane (109-64-8) + 3-chloroprop-1-ene (107-05-1)

Conditions	Yield
aluminum oxide at 160℃; Mechanism; Product distribution; different temperature;

trimethylene oxide (503-30-0) + phosphorus pentachloride (10026-13-8, 874483-75-7) → 1,3-Dichloropropane (142-28-9)

2-methyl-[1,3]dioxane (626-68-6) + phosphorus pentachloride (10026-13-8, 874483-75-7) → 1,3-Dichloropropane (142-28-9) + acetaldehyde (75-07-0)

antimonypentachloride (7647-18-9) + 1,3-dibromo-propane (109-64-8) → 1,3-Dichloropropane (142-28-9)

3-chloropropyl p-toluenesulfonate (632-02-0) + alkyl magnesium chloride → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
With diethyl ether

trimethylene → 1,3-Dichloropropane (142-28-9)

Conditions	Yield
beim Chlorieren;

1-Chloropropane (540-54-5) → 1,3-Dichloropropane (142-28-9) + 1,1-dichloro-propane and 1,2-dichloro-propane

Conditions	Yield
With chlorine at 340℃;
With chlorine at 100℃; in der Gasphase unter der Einwirkung von Licht;
With chlorine at -78℃; in der fluessiger Phase unter der Einwirkung von Licht;

propane (74-98-6) → 1,3-Dichloropropane (142-28-9) + 1.1-dichloro-propane, 1.2-dichloro-propane and 2.2-dichloro-propane

Conditions	Yield
With chlorine at 400℃;
With tetrachloromethane; chlorine at 200℃; under 29420.3 - 36775.4 Torr;
With chlorine at 400℃;

hydrogenchloride (7647-01-0) + 3-chloroprop-1-ene (107-05-1) + dibenzoyl peroxide (94-36-0) → 1,2-Dichloropropane (26198-63-0, 78-87-5) + 1,3-Dichloropropane (142-28-9)

(c-C6H11)2SbLi (1013-90-7) + 1,3-Dichloropropane (142-28-9) → 1,3-bis(dicyclohexylstibino)propane (1057-24-5)

Conditions	Yield
In tetrahydrofuran; diethyl ether addn. of 1,3-dichloropropane in THF over 30 min to a (c-C6H11)2SbLi soln. in ether at -45°C; mixt. treated with aq. NH4Cl, evapn. of the ether;	99%
In tetrahydrofuran; diethyl ether addn. of 1,3-dichloropropane in THF over 30 min to a (c-C6H11)2SbLi soln. in ether at -45°C; mixt. treated with aq. NH4Cl, evapn. of the ether;	99%

1-methyl-1H-imidazole (616-47-7) + 1,3-Dichloropropane (142-28-9) → 1,1'-dimethyl-3,3'-(1,3-trimethylene)bisimidazolium dichloride

Conditions	Yield
In chloroform at 60℃; under 14251400 Torr; for 24h; Pressure; Menshutkin Reaction; High pressure; Autoclave;	99%
at 110℃; for 6h; neat (no solvent);	92%
In methanol for 24h; Reflux;
In methanol for 24h; Reflux;

1,2-dimethyl-1H-imidazole (1739-84-0) + 1,3-Dichloropropane (142-28-9) → 1,3-bis(1,2-dimethylimidazolium-3-yl)propane dichloride

Conditions	Yield
In chloroform at 60℃; under 14251400 Torr; for 24h; Kinetics; Pressure; Time; Menshutkin Reaction; High pressure; Autoclave;	99%

1,3-Dichloropropane (142-28-9) + dicyclohexylphosphane (829-84-5) → 1,3-bis(dicyclohexylphosphine)propane (103099-52-1)

Conditions	Yield
Stage #1: dicyclohexylphosphane With n-butyllithium In tetrahydrofuran at -78 - 20℃; for 1.25h; Inert atmosphere; Schlenk technique; Stage #2: 1,3-Dichloropropane In tetrahydrofuran at -78 - 20℃; for 2h; Inert atmosphere; Schlenk technique;	97%

phthalimide (136918-14-4) + ethyl acetoacetate (141-97-9) + 1,3-Dichloropropane (142-28-9) → ethyl 2-acetyl-5-(1,3-dioxo-1,3-dihydro-2-isoindolyl)pentanoate (55747-45-0)

Conditions	Yield
Stage #1: phthalimide With potassium carbonate In acetonitrile at 20℃; for 0.5h; Stage #2: 1,3-Dichloropropane With sodium iodide In acetonitrile at 58 - 60℃; for 5.5h; Stage #3: ethyl acetoacetate In acetonitrile at 20℃; for 7h; Reagent/catalyst;	96.2%

theobromine / (83-67-0) + 1,3-Dichloropropane (142-28-9) → 1-(3-chloropropyl)-3,7-dimethyl-2,3,6,7-tetrahydro-1H-2,6-purinedione (74409-52-2)

Conditions	Yield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride for 2h; Heating;	96%

sodium formate (141-53-7) + 1,3-Dichloropropane (142-28-9) → 1,3-propanediol diformate (1727-40-8)

Conditions	Yield
tetrabutylammomium bromide at 115℃; for 1.5h;	96%

1,3-Dichloropropane (142-28-9) + 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione (61717-82-6) → propane-1,3-diyl bis(2-iodobenzoate)

Conditions	Yield
With tetrabutylammomium bromide In dimethyl sulfoxide at 80℃;	96%

4-Methoxyphenylacetic acid (104-01-8) + 1,3-Dichloropropane (142-28-9) → 3-chloropropyl 2-(4-methoxyphenyl)acetate (98128-28-0)

Conditions	Yield
With potassium carbonate In dimethyl sulfoxide at 45℃; for 3h;	96%

dimethylenecyclourethane (497-25-6) + 1,3-Dichloropropane (142-28-9) → 3-(3-chloro-1-propyl)-2-oxazolidinone (10127-86-3)

Conditions	Yield
With NaH In dichloromethane; N,N-dimethyl-formamide	95%

sodium p-aminobenzoate (555-06-6) + 1,3-Dichloropropane (142-28-9) → propane-1,3-diyl bis(4-aminobenzoate) (57609-64-0)

Conditions	Yield
In N-methyl-acetamide; water	95%
With sodium carbonate; dimethyl sulfoxide; 1,2-dichloro-ethane In water	91.5%

Upstream product

• 50-00-0 formaldehyd 
• 74-85-1 ethene 
• 627-31-6 1,3-Diiodopropane 
• 100-44-7 benzyl chloride 
• 504-63-2 trimethyleneglycol 
• 109-64-8 1,3-dibromo-propane 
• 627-30-5 1-chloro-3-hydroxypropane 
• 20395-25-9 1,1,3-trichloropropane 
• 7647-18-9 antimonypentachloride 
• 632-02-0 3-chloropropyl p-toluenesulfonate 
• 540-54-5 1-Chloropropane 
• 74-98-6 propane 
• 7647-01-0 hydrogenchloride 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 100620-48-2 1-tert-butyl-4-(3-chloropropoxy)benzene 
• 102756-13-8 1,3-bis-(4-tert-butyl-phenoxy)-propane 
• 2117-07-9 hexa-Si-phenyl-Si,Si'-propanediyl-bis-silane 
• 2591-14-2 2-[(3-chloropropyl)sulfanyl]-1,3-benzothiazole 
• 64010-37-3 1-Chloro-4-(3-chloropropoxy)benzene 
• 3722-62-1 1,3-bis-(4-chloro-phenoxy)-propane 
• 69076-29-5 4-(3-chloropropoxy)benzoic acid methyl ester 
• 99810-13-6 3-chloropropyl p-chlorobenzyl sulfide 
• 14366-67-7 1-(3-(4-chlorophenylthio)propylthio)-4-chlorobenzene 
• 101574-12-3 1,3-bis-(4-chloro-benzylsulfanyl)-propane 
• 504-70-1 pyrazolidine 
• 56-18-8 bis(3-aminopropyl)amine 
• 462-38-4 1-chloro-3-fluoro-propane 
• 6940-76-7 1-iodo-3-chloro-propane 

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Laser-Initiated Chain Reactions of Chlorine with Propane and Cyclopropane in Amorphous Films at 77 K

Free radical reactions of chlorine with propane and cyclopropane deposited as amorphous thin films at 77 K have been investigated.Reactions are initiated by pulsed laser photolysis of the chlorine molecules at 308 nm.Product yields and branching ratios have been determined by Fourier transform infrared absorption spectroscopy of the films following irradiation.The Cl2/propane system is characterized by low product yields consistent with a local radical recombination mechanism.However, the Cl2/cyclopropane reaction proceeds via a true chain reaction mechanism involving ring opening of the hydrocarbon.The dominant product of the reaction is the anti,anti conformer of 1,3-dichloropropane.Product yields have been determined as a function of the mole fraction of chlorine in binary mixtures of the reagents.The results are consistent with a simple statistical model for free radical trapping in nonreactive sites within the amorphous films.

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Method and system for producing 1, 3-propylene glycol from 1, 3-dichloropropanol

The invention discloses a method and a system for producing 1, 3-propylene glycol from 1, 3-dichloropropanol. The method comprises the following steps: continuously inputting 1, 3-dichloropropanol into a reaction device provided with a dehydration catalyst for dehydration reaction to prepare 1, 3-dichloropropene; continuously inputting the 1, 3-dichloropropene and hydrogen into a reaction device provided with a hydrogenation catalyst for hydrogenation reaction to prepare 1, 3-dichloropropane; and carrying out hydrolysis reaction on a mixed reaction system containing the 1, 3-dichloropropane, ahydrolysis agent and a solvent to prepare the 1, 3-propylene glycol. According to the method, an intermediate product 1, 3-dichloropropanol of epoxy chloropropane prepared by a cheap glycerol chlorination method is used as a raw material, an important chemical raw material 1, 3-propylene glycol is prepared by three steps of dehydration, hydrogenation and hydrolysis, a new way is provided for preparing 1, 3-propylene glycol from glycerol, and the route has the advantages of mild conditions, low cost, environmental friendliness, economy and the like.

Continuous method for preparation of dihalogenated alkane from diol compound

The invention discloses a continuous method for preparation of dihalogenated alkane from a diol compound. A diol compound and haloid acid are used as the substrate, a microchannel reactor is utilizedto synthesize dihalogenated alkane continuously. Synthesis of the dihalogenated alkane includes the steps of: inputting the diol compound and haloid acid into a mixer respectively by a metering pump at room temperature, conducting premixing, then sending the mixture into a high-temperature section of the microchannel reactor at for reaction, and controlling the reaction temperature by an externalcirculating heat exchange system; at the end of the reaction, letting the product flow out from an outlet of the microchannel reactor and enter a cooling section, letting the cooled material enter a liquid separation kettle for standing and liquid separation, and collecting an organic layer; and preheating the organic layer, then feeding the preheated organic layer into a rectifying tower by a metering pump, controlling the temperature and reflux ratio of a reboiler, and collecting fractions at a specific temperature, thus obtaining the target product in a product collecting tank. The method provided by the invention has the characteristics of high reaction efficiency, safety, environmental protection, convenience and rapidity.

PROCESS FOR HYDROGENATING DICHLOROISOPROPYL ETHER

Convert dichloroisopropyl ether into a halogenated derivative by contacting the dichloroisopropyl ether with a source of hydrogen and a select heterogeneous hydrogenation catalyst under process conditions selected from a combination of a temperature within a range of from 50 degrees centigrade (oC) to 350 oC, a pressure within a range of from atmospheric pressure (0.1 megapascals) to 1000 pounds per square inch (6.9 MPa), a liquid feed volume flow to catalyst mass ratio between 0.5 and 10 L/Kg*h and a volume hydrogen / volume liquid ratio between 100 and 5000 ml gas/ ml liquid. The halogenated derivative is at least one of 1-chloro-2-propanol and 1,2-dichloropropane 1, and glycerin monochlorohydrin.