1420181-01-6

Basic information

• Product Name: (2-butyl-5-nitro-1-benzofuran-3-yl)[4-(3,3-diethoxypropoxy)phenyl]methanone
• Synonyms: (2-butyl-5-nitro-1-benzofuran-3-yl)[4-(3,3-diethoxypropoxy)phenyl]methanone
• CAS NO: 1420181-01-6
• Molecular Weight: 469.535
• Mol File: 1420181-01-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-butyl-5-nitro-1-benzofuran-3-yl)[4-(3,3-diethoxypropoxy)phenyl]methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-butyl-5-nitro-1-benzofuran-3-yl)[4-(3,3-diethoxypropoxy)phenyl]methanone(1420181-01-6)
• EPA Substance Registry System: (2-butyl-5-nitro-1-benzofuran-3-yl)[4-(3,3-diethoxypropoxy)phenyl]methanone(1420181-01-6)

Safety Data

• Hazardous Substances Data: 1420181-01-6(Hazardous Substances Data)

Upstream product

• 141645-16-1 2-n-butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran 
• 35573-93-4 3-chloro-1,1-diethoxy-propane 

Downstream Products

• 141626-36-0 dronedarone 
• 1420180-98-8 N-(2-butyl-3-[4-(3-oxopropoxy)benzoyl]-1-benzofuran-5-yl)methanesulfonamide 
• 1420180-99-9 N-(2-butyl-3-[4-(3,3-diethoxypropoxy)benzoyl]-1-benzofuran-5-yl)methanesulfonamide 
• 1420181-00-5 (5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone 

Relevant articles and documents

REDUCTIVE ANIMATION PROCESS FOR PREPARATION OF DRONEDARONE USING ALDEHYDE INTERMEDIARY COMPOUND

The invention relates to a novel process for preparation of dronedarone of formula (I) and pharmaceutically acceptable salts thereof, characterized in that the compound of formula (II) is reacted with dibutylamine of formula (III), under reducing circumstances, and the obtained product is isolated and, if desired, converted into a pharmaceutically acceptable salt thereof, The invention also relates to some novel intermediary compounds and the preparation thereof.