14204-23-0

Basic information

• Product Name: 2,5-Pyrrolidinedione, 1-[(phenylmethyl)thio]-
• CAS NO: 14204-23-0
• Molecular Formula: C11H11NO2S
• Molecular Weight: 221.28
• Mol File: 14204-23-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2,5-Pyrrolidinedione, 1-[(phenylmethyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Pyrrolidinedione, 1-[(phenylmethyl)thio]-(14204-23-0)
• EPA Substance Registry System: 2,5-Pyrrolidinedione, 1-[(phenylmethyl)thio]-(14204-23-0)

Safety Data

• Hazardous Substances Data: 14204-23-0(Hazardous Substances Data)

Usage

General Description

2,5-Pyrrolidinedione, 1-[(phenylmethyl)thio]- is a chemical compound with a molecular formula of C12H13NO2S. It is also known by its common name, Thio-2-aminoglutethimide. 2,5-Pyrrolidinedione, 1-[(phenylmethyl)thio]- is a derivative of glutethimide, a sedative and hypnotic medication that was once used for the treatment of insomnia. The addition of a thiol group makes Thio-2-aminoglutethimide potentially useful for various medical and pharmaceutical applications. It may have potential anti-tumor and anti-cancer properties, and has been studied for its effects on hormone production and regulation in the body. Additionally, it has been investigated for its potential use as an inhibitor for certain enzymes and as a precursor for the synthesis of other chemical compounds.

Upstream product

• 150-60-7 dibenzyl disulphide 
• 538-74-9 dibenzyl sulfide 
• 123-56-8 Succinimide 
• 100-53-8 phenylmethanethiol 
• 128-08-5 N-Bromosuccinimide 
• 100-39-0 benzyl bromide 
• 23728-85-0 benzyl(tributyltin) sulfide 
• 128-09-6 N-chloro-succinimide 

Downstream Products

• 2976-37-6 benzyl trichloromethyl thioether 
• 1394951-63-3 C₂₈H₂₃NOS 
• 1394951-86-0 C₂₈H₂₃NOS 
• 1394951-98-4 C₂₈H₂₃NO₃S 
• 1394951-64-4 C₂₈H₂₂FNOS 
• 1394951-65-5 C₂₈H₂₂ClNOS 

Relevant articles and documents

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h-BN@Copper(II) nanomaterial catalyzed cross-coupling reactions between sulfoximines and N-(phenylthio)-succinimide under mild condition

A novel and efficient method for the synthesis of N-S substituted sulfoximines has been established with h-BN-supported copper(II) nanomaterial as the catalyst. Catalyzed by this heterogeneous catalyst, the desired products were obtained with wide scope of substrates, good to excellent yields, free ligand and low-toxicity solvent. Moreover, after being reused ten times, there is almost no significant loss of its catalytic activity.

Catalytic Electrophilic Thiocarbocyclization of Allenes

An efficient approach via catalytic electrophilic thiocarbocyclization of allenes to construct indene-based sulfides with excellent regioselectivities is disclosed. The reactions were carried out at low temperatures by selenide catalysis in the presence o

"On water" catalytic enantioselective sulfenylation of deconjugated butyrolactams

The first catalytic enantioselective α-sulfenylation of deconjugated butyrolactams has been developed using dimeric cinchona alkaloids as catalysts in a water-enriched reaction medium. Highly substituted and densely functionalized γ-lactams, bearing a qua