1421252-90-5

Basic information

• Product Name: 3,5-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole
• Synonyms: 3,5-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole;3,5-dimethyl-1-[(4-methylphenyl)sulfonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-Indazole;EOS-60735
• CAS NO: 1421252-90-5
• Molecular Formula: C₂₂H₂₇BN₂O₄S
• Molecular Weight: 426.33678
• Mol File: 1421252-90-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 594.3±60.0 °C(Predicted)
• Appearance: /
• Density: 1.21±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -3.05±0.50(Predicted)
• CAS DataBase Reference: 3,5-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole(1421252-90-5)
• EPA Substance Registry System: 3,5-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole(1421252-90-5)

Safety Data

• Hazardous Substances Data: 1421252-90-5(Hazardous Substances Data)

Usage

General Description

3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole is a chemical compound with potential applications in pharmaceutical and chemical research. It is a tosyl-protected boronic acid derivative of 1H-indazole, possessing a methyl substituent at the 3 and 5 positions, and a 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) group at the 4 position. 3,5-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole is used as a building block in organic synthesis, particularly in the development of new drugs and agrochemicals. Its unique structure and reactivity make it a valuable tool for the development of novel molecules with potential biological and industrial applications.

Upstream product

• 261762-63-4 1-(2-chloro-6-fluoro-3-methylphenyl)ethanone 
• 1421252-92-7 4-chloro-3,5-dimethyl-1-tosyl-1H-indazole 
• 73183-34-3 bis(pinacol)diborane 
• 1421252-91-6 4-chloro-3,5-dimethyl-1H-indazole 

Downstream Products

• 1421254-21-8 (R)-2-(3,5-dimethyl-1-tosyl-1H-indazol-4-yl)-4-(4-methoxy-3,3-dimethylpiperidin-1-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine 
• 1421254-22-9 (R)-1-cyclopropyl-3-(2-(3,5-dimethyl-1-tosyl-1H-indazol-4-yl)-4-(4-methoxy-3,3-dimethylpiperidin-1-yl)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)propane-1,3-dione 
• 1421254-23-0 (R)-6-(3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)-2-(3,5-dimethyl-1-tosyl-1H-indazol-4-yl)-4-(4-methoxy-3,3-dimethylpiperidin-1-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine 
• 1421254-24-1 (R)-6-(4-chloro-3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)-2-(3,5-dimethyl-1-tosyl-1H-indazol-4-yl)-4-(4-methoxy-3,3-dimethylpiperidin-1-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine 
• 1421249-72-0 2-(3,5-dimethyl-1H-indazol-4-yl)-6-(5-isopropyl-2-methylphenyl)-4-((3-endo)-3-methoxy-8-azabicyclo[3.2.1]octan-8-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine 
• 1421254-68-3 2-(3,5-dimethyl-1-tosyl-1H-indazol-4-yl)-6-(5-isopropyl-2-methylphenyl)-4-((3-endo)-3-methoxy-8-azabicyclo[3.2.1]octan-8-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine 
• 1421254-20-7 (R)-6-benzyl-2-(3,5-dimethyl-1-tosyl-1H-indazol-4-yl)-4-(4-methoxy-3,3-dimethylpiperidin-1-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine 

Relevant articles and documents

TETRAHYDROPYRIDO-PYRIDINE AND TETRAHYDROPYRIDO-PYRIMIDINE COMPOUNDS AND USE THEREOF AS C5A RECEPTOR MODULATORS

The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.