14213-10-6

Basic information

• Product Name: 1H-Tetrazole,1-(3-nitrophenyl)-
• Synonyms: 5-(4-Nitrophenyl)tetrazole
• CAS NO: 14213-10-6
• Molecular Formula: C₇H₅N₅O₂
• Molecular Weight: 191.149
• Mol File: 14213-10-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 435.3 °C at 760 mmHg
• Flash Point: 217.1 °C
• Density: 1.534 g/cm³
• CAS DataBase Reference: 1H-Tetrazole,1-(3-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazole,1-(3-nitrophenyl)-(14213-10-6)
• EPA Substance Registry System: 1H-Tetrazole,1-(3-nitrophenyl)-(14213-10-6)

Safety Data

• Hazardous Substances Data: 14213-10-6(Hazardous Substances Data)

Usage

Tetrazole derivative

A tetrazole ring with a nitrophenyl group attached This compound is derived from a tetrazole ring (a 5-membered ring with 4 nitrogen atoms and 1 carbon atom) and has a nitrophenyl group (a phenyl group with a nitro group) attached to it.

Applications in synthesis

Pharmaceutical, dyes, and other organic compounds 1H-Tetrazole, 1-(3-nitrophenyl)is commonly used as a building block in the synthesis of various pharmaceuticals, dyes, and other organic compounds.

Versatile building block

Preparation of heterocyclic compounds This compound is a useful building block for the preparation of various heterocyclic compounds (compounds containing a ring of atoms with at least one non-carbon atom).

Chemical modifications

Utilization of the 3-nitrophenyl group The 3-nitrophenyl group in this compound can be used for further chemical modifications, making it a valuable and versatile building block in organic synthesis.

Potential applications

Corrosion inhibitor and energetic material 1H-Tetrazole, 1-(3-nitrophenyl)has potential applications as a corrosion inhibitor (a substance that slows down or prevents the corrosion of metals) and as an energetic material due to its explosive properties.

Upstream product

• 99-65-0 meta-dinitrobenzene 
• 99-09-2 3-nitro-aniline 
• 149-73-5 trimethyl orthoformate 
• 122-51-0 orthoformic acid triethyl ester 
• 99-61-6 3-nitro-benzaldehyde 

Downstream Products

• 847606-71-7 N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[3-(1H-tetrazol-1-yl)phenyl]hydrazinecarboxamide 
• 847606-73-9 N'-[4-chloro-3-(trifluoromethyl)phenyl]-N-[3-(1H-tetrazol-1-yl)phenyl]glycinamide 
• 847606-72-8 (3-tetrazol-1-yl-phenyl)-hydrazine hydrochloride 
• 125620-14-6 1,3-phenylene-bis-(1H)-tetrazole 
• 133638-22-9 3-Tetrazol-1-yl-phenyl-cyanamide 
• 13463-91-7 N,N'-m-phenylene-di-carbamonitrile 
• 14213-12-8 3-(tetrazol-1-yl)phenylamine 

Relevant articles and documents

Azasydnone-novel "green" building block for designing high energetic compounds

The discovery of novel explosophoric building blocks for the construction of energetic compounds is extremely rare. Here, based on the comparative experimental properties and computational analysis of compounds where nitroaryl backbones were bonded with various nitrogen/oxygen-rich groups, it is shown that compounds having the azasydnone group possess higher density, detonation performance and thermal stability than their corresponding nitro, azido and tetrazole-analogs. All of these properties, as well as the oxygen balanced content of the "green" nitrogen rich endothermic unit make them an attractive explosophoric building block in the field of energetic materials chemistry.

Five-membered N-Heterocycles Synthesis Catalyzed by Nano-silica Supported Copper(II)–2-imino-1,2-diphenylethan-1-ol Complex

Abstract: In this study, a new amino functionalized nano silica was synthesized using 2-hydroxy-1,2-diphenylethan-1-one. The new 2-hydroxy-1,2-diphenylethan-1-one@amino functionalized nano-silica was used as a support material for copper(II) catalyst. This composite was characterized by various techniques such as transmission electron microscopy, field emission scanning electron microscope, X-ray powder diffraction, inductively coupled plasma, energy dispersive X-ray spectroscopy, thermal gravimetric and FT-IR analysis and its particles size was estimated to be between 20 and 30?nm. The catalyst was tested in the N-heterocycles synthesis via C–N bond forming reactions. The catalyst displayed outstanding catalytic activity for all reactions under mild conditions. Finally, the nano heterogeneous copper catalyst is recoverable up to 12 times without any significant leaching which indicated that the heterogeneous catalyst is stable and very active under the applied conditions. Graphical Abstract: [Figure not available: see fulltext.]

Trifluoromethanesulfonimide catalysed synthesis of 1-substituted-1H-1,2,3,4-tetrazoles using glycerol as green solvent at room temperature

A direct synthetic protocol is developed for the synthesis of 1-substituted-1H-1,2,3,4-tetrazoles via a three-component condensation of primary amines, triethyl orthoformate and sodium azide in the presence of 5 mol% of trifluoromethanesulfonimide (HNTf2) in glycerol at room temperature with good to excellent yields.