142285-26-5

Basic information

• Product Name: (2S^*,7S^*)-2-(3,5-dinitrobenzoyl)oxymethyl-7-hexyloxepane
• CAS NO: 142285-26-5
• Molecular Weight: 408.452
• Mol File: 142285-26-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S^*,7S^*)-2-(3,5-dinitrobenzoyl)oxymethyl-7-hexyloxepane(CAS DataBase Reference)
• NIST Chemistry Reference: (2S^*,7S^*)-2-(3,5-dinitrobenzoyl)oxymethyl-7-hexyloxepane(142285-26-5)
• EPA Substance Registry System: (2S^*,7S^*)-2-(3,5-dinitrobenzoyl)oxymethyl-7-hexyloxepane(142285-26-5)

Safety Data

• Hazardous Substances Data: 142285-26-5(Hazardous Substances Data)

Upstream product

• 123151-65-5 (2S^*,7R^*)-2-hexyl-7-hydroxymethyloxepane 
• 99-33-2 3,5-dinitrobenoyl chloride 
• 16429-21-3 6-hexyl-ε-caprolactone 
• 123151-65-5 (2S^*,7S^*)-2-hexyl-7-hydroxymethyloxepane 
• 142285-20-9 2-Hexyl-7-methylene-oxepane 
• 142285-21-0 (2R,7R)-7-Hexyl-oxepane-2-carbaldehyde 

Relevant articles and documents

Synthesis of Medium Ring Ethers. Part 2. Synthesis of the Fully Saturated Carbon Skeleton of Laurencia Non-terpenoid Ether Metabolites Containing Seven-, Eight- and Nine-membered Rings

A general method for the construction of medium ring ethers is described in which a 2-substituted cycloalkanone was subjected to a Baeyer-Villiger ring expansion to the lactone, Tebbe methylenation of which afforded the enol ether which was subjected to a hydroboration-oxidation sequence to afford the 2,n-disubstituted oxacycle (n = ring size).Application of this procedure has led to efficient syntheses of the fully saturated skeletons corresponding to the naturally occurring Laurencia metabolites containing 2,n-dialkyl substituted seven- (isolaurepan), eight- (lauthisan and laurenan) and nine-membered (obtusan) ethers.