142422-31-9Relevant articles and documents
Stereoselective syntheses of substituted 5,6-dihydro-2(1H)-pyridinones in polyphosphate media
Marson,Grabowska,Fallah,Walsgrove,Eggleston,Baures
, p. 291 - 296 (2007/10/02)
δ-Lactams have been synthesized with excellent stereocontrol of substituents by condensing 3-alkenamides with aryl aldehydes in polyphosphoric ester. The scope of the condensation of 3-alkenamides with aryl aldehydes in several phosphate media is examined, and a rationale is proposed regarding γ-lactam versus δ-lactam formation.