142437-67-0

Basic information

• Product Name: AMTHAMINE DIHYDROBROMIDE
• Synonyms: AMTHAMINE;AMTHAMINE DIHYDROBROMIDE;2-AMINO-5-(2-AMINOETHYL)-4-METHYLTHIAZOLE DIHYDROBROMIDE;2-AMINO-4-METHYL-5-THIAZOLEETHANAMINE DIHYDROBROMIDE;2-AMINO-4-METHYLTHIAZOLE-5-ETHANAMINE 2HBR;2-Amino-4-methylthiazole-5-ethanamine;5-ThiazoleethanaMine, 2-aMino-4-Methyl-;5-(2-Aminoethyl)-4-methylthiazol-2-amine
• CAS NO: 142437-67-0
• Molecular Formula: C6H13Br2N3S
• Molecular Weight: 319.06
• Product Categories: Histamine receptor
• Mol File: 142437-67-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 325.5 °C at 760 mmHg
• Flash Point: 150.6 °C
• Appearance: /
• Density: 1.236 g/cm³
• Vapor Pressure: 1.89E-06mmHg at 25°C
• Storage Temp.: Desiccate at -20°C
• CAS DataBase Reference: AMTHAMINE DIHYDROBROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: AMTHAMINE DIHYDROBROMIDE(142437-67-0)
• EPA Substance Registry System: AMTHAMINE DIHYDROBROMIDE(142437-67-0)

Safety Data

• Hazardous Substances Data: 142437-67-0(Hazardous Substances Data)

Usage

Description

Amthamine dihydrobromide is a chemical compound that functions as an extremely selective H2 agonist. It is known for its ability to suppress the release of serotonin, making it a potential candidate for various applications in the pharmaceutical and medical industries.

Uses

Used in Pharmaceutical Applications:
Amthamine dihydrobromide is used as a selective H2 agonist for the suppression of serotonin release. This property makes it a valuable compound in the development of treatments for conditions related to serotonin imbalances, such as anxiety, depression, and other mood disorders.
Used in Medical Research:
In the field of medical research, Amthamine dihydrobromide can be utilized as a research tool to study the role of H2 agonists in various physiological processes. Its selective nature allows for a more targeted investigation of the effects of H2 agonists on serotonin release and related pathways.
Used in Drug Development:
Amthamine dihydrobromide's ability to suppress serotonin release can be leveraged in the development of new drugs for the treatment of serotonin-related disorders. By understanding its mechanism of action and potential interactions with other compounds, researchers can design more effective and targeted therapies for patients in need.

Biological Activity

Highly selective H 2 agonist, slightly more potent than histamine itself. Only a weak antagonist at H 3 and has no activity at H 1 receptors. Induces vasodilation of cerebral arteries and decreases myogenic tone in vitro .

InChI:InChI=1/C6H11N3S.2BrH/c1-4-5(2-3-7)10-6(8)9-4;;/h2-3,7H2,1H3,(H2,8,9);2*1H