142439-99-4 Usage
Description
4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-6-SULPHATE-BETA-D-GLUCOPYRANOSIDE, also known as 4-MU-GlcNAc6S, is a synthetic compound that serves as a fluorescent substrate for specific enzymes. It is widely utilized in the field of biochemistry and molecular biology for the detection and analysis of enzyme activity, particularly for isoenzyme A of N-acetyl-β-D-glucosaminidase (Hexosaminidase A). 4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-6-SULPHATE-BETA-D-GLUCOPYRANOSIDE is characterized by its ability to emit fluorescence upon enzymatic hydrolysis, making it a valuable tool for research and diagnostic purposes.
Uses
Used in Biochemical Research:
4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-6-SULPHATE-BETA-D-GLUCOPYRANOSIDE is used as a fluorescent substrate for the detection and analysis of isoenzyme A of N-acetyl-β-D-glucosaminidase (Hexosaminidase A) activity. It is particularly useful in studying the enzyme's role in various biological processes and its involvement in certain genetic disorders.
Used in Diagnostic Applications:
In the medical field, 4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-6-SULPHATE-BETA-D-GLUCOPYRANOSIDE is used as a diagnostic tool for the identification and characterization of genetic disorders related to the Hexosaminidase A enzyme. Its ability to produce a fluorescent signal upon enzymatic hydrolysis allows for the accurate assessment of enzyme activity, which can be indicative of specific diseases or conditions.
Used in Pharmaceutical Research:
4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-6-SULPHATE-BETA-D-GLUCOPYRANOSIDE is also employed in the pharmaceutical industry for the development of new drugs targeting the Hexosaminidase A enzyme. By understanding the enzyme's activity and its role in various diseases, researchers can design and synthesize potential therapeutic agents that modulate its function, leading to novel treatments for related conditions.
Used in the Study of Sandhoff Disease:
In the field of genetic research, 4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-6-SULPHATE-BETA-D-GLUCOPYRANOSIDE is used as a tool for the characterization of the mutant β-subunit of β-hexosaminidase responsible for the adult form of Sandhoff disease with the motor neuron disease phenotype. 4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-6-SULPHATE-BETA-D-GLUCOPYRANOSIDE aids in understanding the molecular basis of the disease and the development of potential therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 142439-99-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,4,3 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 142439-99:
(8*1)+(7*4)+(6*2)+(5*4)+(4*3)+(3*9)+(2*9)+(1*9)=134
134 % 10 = 4
So 142439-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C18H21NO11S.Na/c1-8-5-14(21)29-12-6-10(3-4-11(8)12)28-18-15(19-9(2)20)17(23)16(22)13(30-18)7-27-31(24,25)26;/h3-6,13,15-18,22-23H,7H2,1-2H3,(H,19,20)(H,24,25,26);/q;+1/p-1/t13-,15-,16-,17-,18-;/m1./s1
