142564-53-2

Basic information

• Product Name: 5-tert-Butyl-2-nitro-phenylamine
• Synonyms: 5-tert-Butyl-2-nitro-phenylamine
• CAS NO: 142564-53-2
• Molecular Formula: C₁₀H₁₄N₂O₂
• Molecular Weight: 194.24
• Mol File: 142564-53-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-tert-Butyl-2-nitro-phenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-tert-Butyl-2-nitro-phenylamine(142564-53-2)
• EPA Substance Registry System: 5-tert-Butyl-2-nitro-phenylamine(142564-53-2)

Safety Data

• Hazardous Substances Data: 142564-53-2(Hazardous Substances Data)

Upstream product

• 253185-03-4 tert-butylbenzene 
• 261711-98-2 N-(5-tert-butyl-2-nitro-phenyl)-2,2,2-trifluoro-acetamide 
• 23278-20-8 N-(2,5-di-tert-butyl-phenyl)-acetamide 
• 38382-35-3 N-[3-(tert-butyl)phenyl]acetamide 
• 5369-19-7 3-tert-butylaniline 
• 3282-56-2 4-tert-butylnitrobenzene 
• 6933-55-7 acetic acid-(5-tert-butyl-2-nitro-anilide) 

Downstream Products

• 261712-05-4 5-tert-Butyl-2-nitro-4-thiocyanato-phenylamine 
• 90869-73-1 4-(tert-butyl)-2-chloronitrobenzene 
• 261712-19-0 toluene-4-thiosulfonic acid S-(4,5-bis-tert-butoxycarbonylamino-2-tert-butyl-phenyl) ester 
• 261712-13-4 (2-tert-butoxycarbonylamino-4-tert-butyl-5-thiocyanato-phenyl)-carbamic acid tert-butyl ester 
• 261712-35-0 (2-tert-butoxycarbonylamino-4-tert-butyl-5-mercapto-phenyl)-carbamic acid tert-butyl ester 
• 261712-31-6 N-(5-tert-butyl-2-nitro-4-thiocyanato-phenyl)-oxalamic acid methyl ester 
• 261712-23-6 Toluene-4-thiosulfonic acid S-(4,5-diamino-2-tert-butyl-phenyl) ester 
• 261712-09-8 4-tert-butyl-5-thiocyanato-benzene-1,2-diamine 
• 22385-83-7 4-t-butyl-1,2-dinitrrobenzene 
• 5651-77-4 5-tert-butyl-2-nitrophenol 

Relevant articles and documents

HIV protease inhibitors

The present invention relates to novel dihydropyrones with tethered heterocycles having improved pharmacologic properties which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The dihydropyrones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of the dihydropyrones and intermediates useful in the preparation of the final compounds.

A convenient copper-catalyzed direct animation of nitroarenes with 9-alkylhydroxylamines

O-Alkylhydroxylamines, particularly O-methylhydroxylamine, aminate nitroarenes in the presence of a strong base and a copper catalyst to give aminonitroarenes in good yields, ortho- or para-Animation with respect to the nitro group takes place, and in some cases the ortho-aminated product is preferentially obtained. With 3-substituted nitrobenzenes where the substituent has a lone pair of electrons, preferential amination occurs at the 2-position to give the sterically most congested 3c-f, 14 and 22g.

Copper-catalyzed direct amination of nitrobenzenes with O-alkylhydroxylamines

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