1426121-77-8

Basic information

• Product Name: C₃₂H₅₀N₂
• Synonyms: C₃₂H₅₀N₂
• CAS NO: 1426121-77-8
• Molecular Weight: 462.762
• Mol File: 1426121-77-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₂H₅₀N₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₅₀N₂(1426121-77-8)
• EPA Substance Registry System: C₃₂H₅₀N₂(1426121-77-8)

Safety Data

• Hazardous Substances Data: 1426121-77-8(Hazardous Substances Data)

Upstream product

• 571184-11-7 2-pent-1-ynyl-benzaldehyde 
• 627-19-0 1-Pentyne 
• 6630-33-7 ortho-bromobenzaldehyde 
• 59059-43-7 2-n-pentylbenzaldehyde 

Relevant articles and documents

Antimycobacterial activity evaluation, time-kill kinetic and 3D-QSAR study of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives

A series of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives were synthesized and evaluated for their antitubercular activity. Some of the compounds exhibited potent activity against Mycobacterium tuberculosis H37Rv. One of the compound having t-butyl at para position of the benzene ring showed excellent activity even better than the standard drug ethambutol with MIC value 1.1 ± 0.2 μM. The time-kill kinetics study of two most active compounds showed rapid killing of the M. tuberculosis within 4 days. Additionally atom-based quantitative structure-activity relationship (QSAR) model was developed that gave a statistically satisfying result (R2) = 0.92, Q2 = 0.75, Pearson-R = 0.96 and effectively predicts the anti-tuberculosis activity of training and test set compounds.