142717-44-0

Basic information

• Product Name: ethyl 2-[4-(benzyloxy)phenoxy]acetate
• Synonyms: ethyl 2-[4-(benzyloxy)phenoxy]acetate
• CAS NO: 142717-44-0
• Molecular Formula: C₁₇H₁₈O₄
• Molecular Weight: 286.33
• Mol File: 142717-44-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 410.6°C at 760 mmHg
• Flash Point: 180.6°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 5.95E-07mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: ethyl 2-[4-(benzyloxy)phenoxy]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-[4-(benzyloxy)phenoxy]acetate(142717-44-0)
• EPA Substance Registry System: ethyl 2-[4-(benzyloxy)phenoxy]acetate(142717-44-0)

Safety Data

• Hazardous Substances Data: 142717-44-0(Hazardous Substances Data)

Usage

General Description

Ethyl 2-[4-(benzyloxy)phenoxy]acetate is a chemical compound with the molecular formula C18H18O4. It is a clear, colorless liquid with a slightly sweet odor. ethyl 2-[4-(benzyloxy)phenoxy]acetate is commonly used as a fragrance ingredient in perfumes, soaps, and other personal care products. It is also utilized in the pharmaceutical industry as an intermediate in the synthesis of various drugs. Ethyl 2-[4-(benzyloxy)phenoxy]acetate is considered to be relatively safe for use in these applications, with low levels of toxicity reported in animal studies. However, as with any chemical, it is important to handle and use this compound with care and in accordance with safety guidelines.

InChI:InChI=1/C17H18O4/c1-2-19-17(18)13-21-16-10-8-15(9-11-16)20-12-14-6-4-3-5-7-14/h3-11H,2,12-13H2,1H3

Upstream product

• 103-16-2 4-Benzyloxyphenol 
• 105-39-5 chloroacetic acid ethyl ester 
• 64-17-5 ethanol 
• 38559-92-1 2-(4-Benzyloxyphenoxy)ethanoic acid 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 1489287-92-4 1-(4-benzyloxyphenoxyacetyl)-4-(4-phenylbenzyl)-thiosemicarbazide 
• 380336-87-8 4-benzyloxyphenoxyacetic acid hydrazide 
• 845743-65-9 ethyl 2-({2-[2-(4-{(2S)-2-hydroxy-3-[(methylethyl)amino]propoxy}phenoxy)acetylamino]ethoxy}methyl)-4-(2-chlorophenyl)-5-cyano-6-metllyl-1,4-dihydropyridine-3-carboxylate 
• 845744-03-8 ethyl 4-(2-chlorophenyl)-5-cyano-2-({2-[2-(4-hydroxyphenoxy)acetylamino]ethoxy}methyl)-6-methyl-1,4-dihydropyridine-3-carboxylate 
• 142717-45-1 4-Propylphenyl 2-(4-benzyloxyphenoxy)ethanoate 
• 142741-91-1 4-Propylphenyl 2-(4-hydroxyphenoxy)ethanoate 

Relevant articles and documents

Campestarenes: New building blocks with 5-fold symmetry

Campestarene is a planar, shape-persistent macrocycle with 5-fold symmetry. A range of derivatives bearing peripheral functional groups suitable for generating supramolecular interactions has been designed and synthesised for potential applications in creating 2D quasicrystal molecular assemblies. The new campestarene derivatives bear ester, carboxylic acid, methoxy, bromo, 4-pyridyl, 4-cyanophenyl and 4-phenyl carboxylic acid groups, including further derivatives of the latter two bearing alkyl chains on the phenyl groups to improve solubility. The campestarene derivatives were prepared by reductive condensation of phenol precursors bearing nitro and formyl groups using Na2S2O4. The target functional groups were installed either by pre-cyclisation derivatisation or by synthesis of methoxy-substituted campestarene and subsequent derivatisation. The cyclisation reaction is tolerant of the functional groups introduced. The ten new campestarene derivatives were characterised by NMR spectroscopy and MALDI-TOF MS, although the poor solubility of some examples precluded their detailed characterisation.

PPAR AGONIST COMPOUNDS, PREPARATION AND USES

The present invention relates to novel PPAR agonist compounds as well as pharmaceutical compositions containing them. The compounds according to the invention are of quite particular therapeutic interest, notably for treating diabetes and/or dyslipidemias, as well as for preventing cardiovascular pathologies.

ALKYNYL CONTAINING HYDROXAMIC ACID COMPOUNDS AS TACE INHIBITORS

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