142723-81-7

Basic information

• Product Name: N,N-bis(pyridin-2-ylMethyl)ethanaMine
• Synonyms: N,N-bis(pyridin-2-ylMethyl)ethanaMine
• CAS NO: 142723-81-7
• Molecular Formula: C14H17N3
• Molecular Weight: 227.309
• Mol File: 142723-81-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-bis(pyridin-2-ylMethyl)ethanaMine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-bis(pyridin-2-ylMethyl)ethanaMine(142723-81-7)
• EPA Substance Registry System: N,N-bis(pyridin-2-ylMethyl)ethanaMine(142723-81-7)

Safety Data

• Hazardous Substances Data: 142723-81-7(Hazardous Substances Data)

Usage

General Description

N,N-bis(pyridin-2-ylMethyl)ethanaMine, also known as dipyridylamine, is a chemical compound with the formula C14H16N2. It is a organic compound with two pyridine rings attached to a central amine group. It is commonly used as a ligand in coordination chemistry and is known for its ability to form stable complexes with metal ions. It has been used in various applications, including as a catalyst in organic synthesis, as a reagent in the determination of metals in environmental samples, and as a component in luminescent materials. Dipyridylamine is also known for its toxic effects and should be handled with care.

Upstream product

• 4377-33-7 2-chloromethylpyridine 
• 75-04-7 ethylamine 

Relevant articles and documents

Synthesis of rhenium(I) tricarbonyl complexes with carbohydrate-pendant tridentate ligands and their cellular uptake

Twelve [ReIL(CO)3]n+ complexes with various carbohydrate-pendant ligands L have been prepared and their uptake into HeLa S3 cells were investigated. The ligand library includes: (i) glucose/galactose as the carbohydrate group; (ii) bis(2-pyridylmethyl)amine (DPA), bis(2-quinolylmethyl)amine (DQA), or N-(2-pyridylmethyl)glycine (NPG) as the metal binding component; and (iii) an ethylene chain as a linker between the metal binding site and the O/C-glycosides. Microwave induced plasma mass spectroscopy (MIP-MS) measurements revealed that all complexes were extensively incorporated into the HeLa cells over a 24 h period, and the DQA complexes showed the highest uptake of all the complexes in the series. However, in comparison to the corresponding Re complexes without the pendant carbohydrate functions (prepared with the related ligands LDPA, LDQA, and LNPG), only the NPG complexes exhibited carbohydrate enhanced cellular uptake. Considering their water solubility and cellular uptake properties, the NPG complexes containing an O-glycoside group (L1 and L′1) are the best candidates for enhancing cellular uptake of metal ions. Microscopic analysis with PC-12 cells in the presence of thefluorescent complex [Re(L′7)(CO)3]Cl, revealed that the complex stays in the cell cytosol and cannot penetrate into the nucleus. Copyright