1428-92-8 Usage
Synonyms
4-BCP, nitrogen mustard analogue
Chemical class
Alkylating agent
Structure
Piperazine derivative with two chloroethyl groups
Function
Used in the synthesis of antineoplastic agents
Target
Cross-links DNA, leading to cell death
Potential treatments
Various cancers, including lymphoma and leukemia
Mechanism of action
Inhibits cell growth and induces apoptosis in cancer cells
Toxicity
Highly toxic
Safety precautions
Handle and use with caution in laboratory and medical settings
Adverse effects
Can cause serious side effects due to its toxicity
Check Digit Verification of cas no
The CAS Registry Mumber 1428-92-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,2 and 8 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1428-92:
(6*1)+(5*4)+(4*2)+(3*8)+(2*9)+(1*2)=78
78 % 10 = 8
So 1428-92-8 is a valid CAS Registry Number.
1428-92-8Relevant articles and documents
Design and Synthesis of RNA-Specific Groove-Binding Cations: Implications for Antiviral Drug Design
McConnaughie, Adrian W.,Spychala, Jaroslaw,Zhao, Min,Boykin, David,Wilson, W. David
, p. 1063 - 1069 (1994)
As as initial step in the design of structure-specific RNA-interactive molecules as potential antiviral agents, we have focused on the synthesis of molecules that exhibit strong and preferential binding to douplex RNA.A series of polycationic ligands have
