142927-39-7Relevant articles and documents
Synthesis and NMR Studies of Some Steriodal Isoxazoles
Giacopello, Sergio,Deluca, Monica E.,Seldes, Alicia M.
, p. 891 - 897 (2007/10/02)
A short synthesis of 17α-pregna-2,4-dien-isoxazol-17β-ol (1) is described using mild reaction conditions and with a high overall yield.The equilibrium between keto-enolic forms has been studied by 1H NMR methods.Complete assignments of all the resonances in the 1H and 13C NMR spectra of Danazol have been made using a variety of one and two-dimensional correlation methods. 13C NMR spectra of all the intermediate and related model compounds were also assigned. Key words: Anabolic Agents, Isoxazolinic Steroids, 17α-Pregna-2,4-dien-isoxazol-17β-ol, Synthesis, NMR Spectra