142975-81-3

Basic information

• Product Name: 5'-carboxyl-2',7'-dichlorodihydrofluorescein
• Synonyms: 5'-carboxyl-2',7'-dichlorodihydrofluorescein;5-Carboxy-DCF;2',7'-Dichloro-3',6'-dihydroxy-3-oxo-3H-spiro-[isobenzofuran-1,9'-xanthene]-5-carboxylic acid;5-carboxy-2'7'-dichlorodihydrofluorescein
• CAS NO: 142975-81-3
• Molecular Formula: C21H10Cl2O7
• Molecular Weight: 445.2059
• Mol File: 142975-81-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 732.3°Cat760mmHg
• Flash Point: 396.7°C
• Appearance: /
• Density: 1.86g/cm³
• Storage Temp.: 2-8°C
• Solubility: Insoluble in water, soluble in N,Ndimethylformamide, dimethyl sulfoxide, methanol
• PKA: 4.8(at 22℃)
• CAS DataBase Reference: 5'-carboxyl-2',7'-dichlorodihydrofluorescein(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-carboxyl-2',7'-dichlorodihydrofluorescein(142975-81-3)
• EPA Substance Registry System: 5'-carboxyl-2',7'-dichlorodihydrofluorescein(142975-81-3)

Safety Data

• Hazardous Substances Data: 142975-81-3(Hazardous Substances Data)

Usage

General Description

5'-carboxyl-2',7'-dichlorodihydrofluorescein is a chemical compound commonly used as a fluorescent indicator in biological applications. It is often used to measure reactive oxygen species (ROS) levels, as it can be oxidized by ROS to produce a fluorescent signal. 5'-carboxyl-2',7'-dichlorodihydrofluorescein is derived from dihydrorhodamine 123 and is a non-fluorescent molecule that becomes highly fluorescent upon oxidation. As a result, 5'-carboxyl-2',7'-dichlorodihydrofluorescein is commonly used to study oxidative stress, cellular respiration, and redox signaling in various biological systems. It is a valuable tool for researchers studying oxidative stress-related diseases and conditions, as well as the mechanisms and implications of ROS signaling in cellular processes.